Advances in Pharmaceutical Research:
From Lead Discovery to Drug Manufacturing- Spring 2003
Syllabus Schedule Links Course Homepage
Stuart McCombie, Ph.D., Schering-Plough Research Institute
1. Mild N-Dealkylation of Tertiary, Benzylic Amines with Acid Chlorides: Application to Solid-Phase Chemistry, Pages 3429-3432 Michael W. Miller, Susan F. Vice and Stuart W. McCombie
2. Synthesis of 3-(1-propenyl)- and 3-styrylphthalides using lithiation reactions. Kusurkar, R. S.; Patil, R. N.. Indian Journal of Chemistry, Section B: (1990), 29B(1), 64-5.
3. Transformations of penicillin. Part 8. Preparation of 2-acetylceph-3-em derivatives from carboxy-protected penicillin S-oxides. de Oliveira Baptista M J; Barrett A G; Barton D H; ... JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS 1 (1977), (12), 1477-1500.
5. O-Methylarenehydroxamates as ortho-lithiation directing groups. Titanium(III)-mediated conversion of O-methyl hydroxamates to primary amides Lawrence E. Fisher, ... and Joseph M. Muchowski Journal of Organic Chemistry (1993), 58(14), 3643 - 3647
6. New reactions of hydrazides. Part 1: Directed ortho- and lateral metalation of aromatic carbocyclic and heterocyclic systems McCombie, Stuart W.; Lin, Sue-Ing; Vice, Susan F. Tetrahedron Letters (1999), 40(50), 8767-8770.
7. Chemistry of aminimides McKillip, W. J.; Sedor, E. A.; Culbertson, B. M.; Wawzonek, S. Chemical Reviews (1973), 73(3), 255-81.
8. N-METHOXY-N-METHYLAMIDES AS EFFECTIVE ACYLATING AGENTS NAHM S, WEINREB SM TETRAHEDRON LETTERS 22 (39): 3815-3818 1981
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