All Publications
"Low Part-Per-Trillion, Humidity Resistant Detection of Nitric Oxide Using Microtoroid Optical Resonators"
Yinchao Xu, Allison Stanko, Chloe Cerione, Trevor Lohrey, Euan McLeod, Brian Stoltz, Judith Su.
ChemRxiv. 2023.
"Total Synthesis of Aleutianamine"
Hao Yu, Zachary Sercel, Samir Rezgui, Jonathan Farhi, Scott Virgil, and Brian Stoltz.
J. Am. Chem. Soc. 2023, ASAP.
"Origins of Enhanced Enantioselectivity in the Pd–Catalyzed Decarboxylative Allylic Alkylation of N–Benzoyl Lactams"
Alexander Q. Cusumano, Tianyi Zhang , William A. Goddard III and Brian M. Stoltz.
Catalysts. 2023, 13, 1258.
"Enantioselective 1,3-Dipolar Cycloadditions of α-Methylene Lactams to Construct Spirocycles"
Yuji Nishiura, Kevin J. Gonzalez, Alexander Q. Cusumano and Brian M. Stoltz.
Org. Lett. 2023, 25, 6469–6473.
"Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Lactams: Enantioselective Construction of All-Carbon Quaternary Stereocenters in Saturated Nitrogen-Containing Heterocycles"
Tianyi Zhang, Yuji Nishiura, Alexander Q. Cusumano and Brian M. Stoltz.
Org. Lett. 2023, 25, 6479–6484.
"Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002&ndash2020)"
Alexia N. Kim, Aurapat Ngamnithiporn, Emily Du, and Brian M. Stoltz.
Chem. Rev. 2023, 123, 9447–9496.
"Development of a Nickel-Catalyzed N–N Coupling for the Synthesis of Hydrazides"
Jay P. Barbor, Vaishnavi N. Nair, Kimberly R. Sharp, Trevor D. Lohrey, Sara E. Dibrell, Tejas K. Shah, Martin J. Walsh, Sarah E. Reisman, and Brian M. Stoltz.
J. Am. Chem. Soc. 2023, 145, 15071–15077.
"Tandem Dearomatization/Enantioselective Allylic Alkylation of Pyridines"
Steffen Greßies, Lars Süße, Tyler Casselman, and Brian M. Stoltz.
J. Am. Chem. Soc. 2023, 145, 11907–11913.
"Divergent Catalysis: Catalytic Asymmetric [4+2] Cycloaddition of Palladium Enolates"
Kaylin N. Flesch*, Alexander Q. Cusumano*, Peng-Jui Chen, Christian Santiago Strong, Stephen R. Sardini, Yun E. Du, Michael D. Bartberger, William A. Goddard III, Brian M. Stoltz.
J. Am. Chem. Soc. 2023, 145, 11301–11310.
"Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono–Mannich Reaction"
Alexander W. Rand, Kevin J. Gonzalez, Christopher E. Reimann, Scott C. Virgil, Brian M. Stoltz.
J. Am. Chem. Soc. 2023, 145, 7278–7287.
"Total synthesis of (–)-scabrolide A and (–)-yonarolide"
Nicholas J. Hafeman, Steven A. Loskot, Christopher E. Reimann, Beau P. Pritchett, Scott C. Virgil, Brian M. Stoltz.
Chem. Sci. 2023, 14, 4745–4758.
"Accretion Product Formation in the Self-Reaction of Ethene-Derived Hydroxy Peroxy Radicals"
Sara Edinger Murphy , John D. Crounse , Kristian H. Møller , Samir Rezgui , Nicholas J Hafeman , James Park , Henrik Kjaergaard , Brian M. Stoltz and Paul O Wennberg.
Environ. Sci.: Atmos. 2023, 3, 882–893.
"A Convergent Total Synthesis of (+)-Ineleganolide"
Benjamin M. Gross, Seo-Jung Han, Scott C. Virgil, Brian M. Stoltz.
J. Am. Chem. Soc. 2023, 145, 7763–7767.
"Development of a Non-Directed Petasis-Type Reaction by an Aromaticity-Disrupting Strategy"
Kevin J. Gonzalez, Alexander W. Rand, Brian M. Stoltz.
Angew. Chem. Int. Ed. 2023, 62, e202218921.
"What is a cross-coupling? An argument for a universal definition"
Christopher E. Reimann, Kelly E. Kim, Alexander W. Rand, Farbod A. Moghadam, and Brian M. Stoltz.
Tetrahedron. 2023, 130, 133176.
"Asymmetric Total Synthesis of Havellockate"
Nicholas J. Hafeman*, Melinda Chan*, Tyler J. Fulton, Eric J. Alexy, Steven A. Loskot, Scott. C. Virgil, and Brian M. Stoltz.
J. Am. Chem. Soc. 2022, 144, 20232–20236.
"Investigations of an Unexpected [2+2] Photocycloaddition in the Synthesis of (&ndash)-Scabrolide A from Quantum Mechanics Calculations"
Tianyi Zhang*, Alexander Q. Cusumano*, Nicholas J. Hafeman, Steven A. Loskot, Christopher E. Reimann, Scott C. Virgil, William A. Goddard III, and Brian M. Stoltz.
J. Org. Chem. 2022, 87, 14115–14124.
"Synthesis of enantioenriched 2,2-disubstituted pyrrolidines via sequential asymmetric allylic alkylation and ring contraction"
Elizabeth L. Goldstein, Hirokazu Takada, Yuji Sumii, Katsuaki Baba, Brian M. Stoltz.
Tetrahedron 2022, 14, 132940.
"Part-per-Trillion Trace Selective Gas Detection Using Frequency Locked Whispering-Gallery Mode Microtoroids"
Cheng Li, Trevor Lohrey, Phuong-Diem Nguyen, Zhouyang Min, Yisha Tang, Chang Ge, Zachary P. Sercel, Euan McLeod, Brian M. Stoltz, and Judith Su
ACS Appl. Mater. Interfaces 2022, 14, 37, 42430-42440.
"Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers"
Farbod A. Moghadam, Elliot F. Hicks, Zachary P. Sercel, Alexander Q. Cusumano, Michael D. Bartberger, and Brian M. Stoltz
J. Am. Chem. Soc. 2022, 144, 18, 7983-7987.
"Iridium-catalyzed asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines"
Alexia N. Kim, Aurapat Ngamnithiporn, Michael D. Bartberger, and Brian M. Stoltz
Chem. Sci. 2022, 13, 3227-3232.
"Isotope effects at the origin of life: Fingerprints of the Strecker synthesis"
L. Chimiak, J. Eiler, A. Sessions, C. Blumenfeld, M. Klatte, and B.M. Stoltz
Geochimica et Cosmochimica Acta 2022, 321, 78-98.
"Some unusual transformations of a highly reactive α-bromocaranone"
Adrian E. Samkian, Zachary P. Sercel, Scott C. Virgil, Brian M. Stoltz
Tetrahedron Letters 2022, 89, 153496.
"Late-Stage Diversification: A Motivating Force in Organic Synthesis"
Kelly E. Kim, Alexia N. Kim, Carter J. McCormick, and Brian M. Stoltz
J. Am. Chem. Soc. 2021, 143, 41, 16890-16901.
"Synthesis of Enantioenriched gem-Disubstituted 4-Imidazolidinones by Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation"
Zachary P. Sercel, Alexander W. Sun, and Brian M. Stoltz
Org. Lett. 2021, 23, 16, 6348-6351.
"Identifying the Imperative Role of Metal-Olefin Interactions in Catalytic C-O Reductive Elimination from Nickel(II)"
Trevor D. Lohrey, Alexander Q. Cusumano, William A. Goddard III, and Brian M. Stoltz
ACS Catal. 2021, 11, 16, 10208-10222.
"Synthetic strategy toward ineleganolide: A cautionary tale"
Alexander Q. Cusumano, K.N. Houk, and Brian M. Stoltz
Tetrahedron 2021, 93, 132289.
"The Enantioselective Synthesis of Eburnamonine, Eucophylline, and 16'-epi-Leucophyllidine"
Dr. Christopher E. Reimann, Dr. Aurapat Ngamnithiporn, Dr. Kohei Hayashida, Dr. Daisuke Saito, Katerina M. Korch, and Prof. Dr. Brian M. Stoltz
Angew. Chem. Int. Ed. 2021, 60, 17957-17962.
"Discussion Addendum for: Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids"
Stephen R. Sardini and Brian M. Stoltz
Org. Synth. 2021, 98, 117-130.
"Discovery of novel modulators for the PPARα (peroxisome proliferator activated receptor α): Potential therapies for nonalcoholic fatty liver disease"
Donna D. Yu, Gregg Van Citters, Hongzhi Li, Brian M. Stoltz, and Barry M. Forman
Bioorg. Med. Chem. 2021, 41, 116193.
"A Synthetic Strategy toward Eight-Membered Cyclic Amines by Cycloetherification and Claisen Rearrangement"
Seo-Jung Han, Marchello A. Cavitt, and Brian M. Stoltz
Org. Lett. 2021, 23, 9, 113148.
"A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells"
Gang Zhang, Shan Li, Feng Wang, Amanda C. Jones, Alexander F.G. Goldberg, Benjamin Lin, Scott Virgil, Brian M. Stoltz, Raymond Deshaies, Tsui-en Chou
Eur. J. Med. Chem. 2021, 213, 113148.
"Enantioselective Formation of Quaternary Centers by Allylic Alkylation with First-Row Transition-Metal Catalysts"
Lars Süsse and Brian M. Stoltz
Chem. Rev. 2021, 121, 4084–4099.
"Recent Advances in Homogeneous Catalysts for the Asymmetric Hydrogenation of Heteroarenes"
Alexia N. Kim and Brian M. Stoltz
ACS Catal. 2020, 10, 13834–13851.
"Global Diastereoconvergence in the Ireland-Claisen Rearrangement of Isomeric Enolates: Synthesis of Tetrasubstituted α-Amino Acids"
Tyler J. Fulton,† Alexander Q. Cusumano,† Eric J. Alexy, Yun Emily Du, Haiming Zhang, Ken N. Houk, and Brian M. Stoltz
J. Am. Chem. Soc. 2020, 142, 21938–21947. †Equal Contribution. [Supporting Information].
"The Transition Metal Catalyzed [π2s + π2s + σ2s + σ2s] Pericyclic Reaction: Woodward–Hoffmann Rules, Aromaticity, and Electron Flow"
Alexander Q. Cusumano, William A. Goddard III, and Brian M. Stoltz
J. Am. Chem. Soc. 2020, 142, 19033–19039. [Supporting Information].
This paper was featured in C&EN: Chemists shine light on new way to think about reductive elimination,
and in JACS Spotlights: Follow the Yellow Brick Density.
"Enantioselective Synthesis of Highly Oxygenated Acyclic Quaternary Center-Containing Building Blocks via Palladium-Catalyzed Decarboxylative Allylic Alkylation of Cyclic Siloxyketones"
Aurapat Ngamnithiporn, Toshihiko Iwayama, Michael D. Bartberger, and Brian M. Stoltz
Chem. Sci. 2020, 11, 11068–11071. [Supporting Information].
"Efficient Synthesis of Geminal-Dialkyl Dienes for Olefin Metathesis Polymerization"
William J. Wolf,† Jiaming Li,† Simon C. Jones, Brian M. Stoltz, and Robert H. Grubbs
Macromolecules 2020, 53, 7803–7809. †Equal Contribution. [Supporting Information].
"Synthesis of Carboxylic Acid and Dimer Ester Surrogates to Constrain the Abundance and Distribution of Molecular Products in α-Pinene and β-Pinene Secondary Organic Aerosol"
Christopher M. Kenseth, Nicholas J. Hafeman, Yuanlong Huang, Nathan F. Dalleska, Brian M. Stoltz, and John H. Seinfeld
Environ. Sci. Technol. 2020, 54, 12829–12839. [Supporting Information].
"Reaction Mechanism, Origins of Enantioselectivity, and Reactivity Trends in Asymmetric Allylic Alkylation: A Comprehensive Quantum Mechanics Investigation of a C(sp3)–C(sp3) Cross-Coupling"
Alexander Q. Cusumano, Brian M. Stoltz, and William A. Goddard III
J. Am. Chem. Soc. 2020, 142, 13917–13933. [Supporting Information].
"Catalytic enantioselective synthesis of carbocyclic and heterocyclic spiranes via a decarboxylative aldol cyclization"
Kazato Inanaga,† Marco Wollenburg,† Shoshana Bachman, Nicholas J. Hafeman, and Brian M. Stoltz.
Chem. Sci. 2020, 11, 7390–7395. †Equal Contribution. [Supporting Information].
"Probing Trends in Enantioinduction via Substrate Design: Palladium-Catalyzed Decarboxylative Allylic Alkylation of α-Enaminones"
Douglas C. Duquette, Alexander Q. Cusumano, Louise Lefoulon, Jared T. Moore, and Brian M. Stoltz
Org. Lett. 2020, 22, 4966–4969. [Supporting Information].
"Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Acyclic α-N-Pyrrolyl/Indolyl Ketones"
Rémi Lavernhe, Eric J. Alexy, Haiming Zhang, and Brian M. Stoltz.
Org. Lett. 2020, 22, 4272–4275. [Supporting Information].
"The Total Synthesis of (–)-Scabrolide A"
Nicholas J. Hafeman, Steven A. Loskot, Christopher E. Reimann, Beau P. Pritchett, Scott C. Virgil, and Brian M. Stoltz.
J. Am. Chem. Soc. 2020, 142, 8585–8590. [Supporting Information]. ChemRxiv Preprint.
"Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands"
Doohyun Baek, Huijeong Ryu, Ji Yeon Ryu, Junseong Lee, Brian M. Stoltz, and Sukwon Hong.
Chem. Sci. 2020, 11, 4602–4607. [Supporting Information].
"Enantioselective Total Synthesis of (–)-Myrifabral A and B"
Tyler J. Fulton, Anthony Chen, Michael Bartberger, and Brian Stoltz.
Chem. Sci. 2020, 11, 10802–10806. ChemRxiv Preprint. [Supporting Information].
"Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines"
Alexia N. Kim, Aurapat Ngamnithiporn, Eric R. Welin, Martin T. Daiger, Christian U. Grünanger, Michael D. Bartberger, Scott C. Virgil, and Brian M. Stoltz.
ACS Catal. 2020, 10, 3241–3248. [Supporting Information].
"Enantioselective Synthesis of 15-Deoxy-Δ12,14-Prostaglandin J2"
Jiaming Li, Brian M. Stoltz, and Robert H. Grubbs.
Org. Lett. 2019, 21, 10139–10142. [Supporting Information].
"Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Protected Benzoin-Derived Enol Carbonates"
Rémi Lavernhe, Eric J. Alexy, Haiming Zhang, Brian M. Stoltz.
Adv. Synth. Catal. 2020, 362, 344–347. [Supporting Information].
"Progress toward the Enantioselective Synthesis of Curcusones A–D via a Divinylcyclopropane Rearrangement Strategy"
Austin C. Wright, Chung Whan Lee, and Brian M. Stoltz.
Org. Lett. 2019, 21, 9658–9662. [Supporting Information].
"Cu-Catalyzed Enantioselective Allylic Alkylation with a γ- Butyrolactone-Derived Silyl Ketene Acetal"
Carina Jette, Zhengjia Tong, Ryan Hadt, and Brian Stoltz.
Angew. Chem. Int. Ed. 2020, 59, 2023–2038. [Supporting Information].
"Enantioselective Alkynylation of Trifluoromethyl Ketones Catalyzed by Cation-Binding Salen Nickel Complexes"
Dongseong Park, Carina I. Jette, Jiyun Kim, Woo-ok Jung, Yongmin Lee, Jongwoo Park, Seungyoon Kang, Min Su Han, Brian Stoltz, and Sukwon Hong.
Angew. Chem. Int. Ed. 2020, 59, 775–779. [Supporting Information].
"Synthesis of non-natural cyanthiwigin–gagunin hybrids through late-stage diversification of the cyanthiwigin natural product core"
Kelly E. Kim, Yuka Sakazaki, and Brian M. Stoltz.
Tetrahedron 2020, 76, 130755.
"Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of 1,4-Diazepan-5-ones"
Zachary P. Sercel,† Alexander W. Sun,† and Brian M. Stoltz.
Org. Lett. 2019, 21, 9158–9161. †Equal Contribution. [Supporting Information].
"Stereospecific Overman Rearrangement of Substituted Cyclic Vinyl Bromides: Access to Fully Substituted α-Amino Ketones"
Álvaro Velasco-Rubio, Eric J. Alexy, Makoto Yoritate, Austin C. Wright, and Brian M. Stoltz.
Org. Lett. 2019, 21, 8962–8965. [Supporting Information].
"Modularity: Adding New Dimensions to Total Synthesis"
Alexander W. Sun,† Sebastian Lackner,† and Brian M. Stoltz.
Trends in Chemistry 2019, 1, 630–643.
"Enantioselective Construction of the Tricyclic Core of Curcusones A–D via a Cross-electrophile Coupling Approach"
Austin C. Wright and Brian M. Stoltz.
Chem. Sci. 2019, 10, 10562–10565. [Supporting Information].
"A Small-scale Procedure for Acid-catalyzed Ketal Formation"
Austin C. Wright, Yun Emily Du, and Brian M. Stoltz.
J. Org. Chem. 2019, 84, 11258–11260.
"Incorporation of a chiral gem-disubstituted nitrogen heterocycle yields an oxazolidinone antibiotic with reduced mitochondrial toxicity"
Alexander W. Sun, Philip L. Bulterys, Michael D. Bartberger, Peter A. Jorth, Brendan M. O'Boyle, Scott C. Virgil, Jeff F. Miller, and Brian M. Stoltz.
Bioorg. Med. Chem. Lett. 2019, 29, 2686–2689.
"Unified Enantioselective, Convergent Synthetic Approach toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Synthesis of a Series of Ineleganoloids by Oxidation-State Manipulation of the Carbocyclic Core"
Robert A. Craig, Russell C. Smith, Jennifer L. Roizen, Amanda C. Jones, Scott C. Virgil, and Brian M. Stoltz.
J. Org. Chem. 2019, 84, 7722–7746.
"Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand"
Tyler J. Fulton, Brenda Wu, Eric J. Alexy, Haiming Zhang, and Brian M. Stoltz.
Tetrahedron 2019, 75, 4104–4109. [Supporting Information].
"Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates"
Eric J. Alexy, Tyler J. Fulton, Haiming Zhang, and Brian M. Stoltz.
Chem. Sci. 2019, 10, 5996–6000. [Supporting Information].
"Characterization of reactive organometallic species via MicroED"
Christopher Jones, Matthew Asay, Lee Joon Kim, Jack Kleinsasser, Ambarneil Saha, Tyler J. Fulton, Kevin Berkley, Duilio Cascio, Andrey Malyutin, Matthew Conley, Brian M. Stoltz, Vincent LaVallo, Jose A. Rodriguez, Hosea Nelson.
ACS Cent. Sci. 2019, 5. ChemRXiv Preprint.
"Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes"
Michael M. Yamano, Rachel R. Knapp, Aurapat Ngamnithiporn, Melissa Ramirez, Kendall N. Houk, Brian M. Stoltz, Neil K. Garg.
Angew. Chem. Int. Ed. 2019, 58, 5653–5657. [Supporting Information].
"Discussion Addendum for: The Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2-(2-acetylphenyl)acetate"
Austin C. Wright and Brian M. Stoltz.
Org. Synth. 2019, 96, 80–97.
"An unexpected Ireland–Claisen rearrangement cascade during the synthesis of the tricyclic core of Curcusone C: Mechanistic elucidation by trial-and-error and automatic artificial force-induced reaction (AFIR) computations"
Chung Whan Lee, Buck L. H. Taylor, Galina P. Petrova, Ashay Patel, Keiji Morokuma, K. N. Houk, and Brian M. Stoltz.
J. Am. Chem. Soc. 2019, 141, 6995–7004.
"Development of a catalytic enantioselective synthesis of the guanacastepene and heptemerone tricyclic core"
Andrew M. Harned and Brian M. Stoltz.
Tetrahedron 2019, 75, 3166–3177.
"Palladium-Catalyzed Construction of Quaternary Stereocenters by Enantioselective Arylation of γ-Lactams with Aryl Chlorides and Bromides"
Carina Jette, Irina Geibel, Shoshana Bachman, Masaki Hayashi, Shunya Sakurai, Hideki Shimizu, Jeremy B. Morgan, and Brian Stoltz.
Angew. Chem. Int. Ed. 2019, 58, 4297–4301. [Supporting Information].
"Atroposelective Synthesis of PINAP via Dynamic Kinetic Asymmetric Transformation"
Seo-Jung Han, Vikram Bhat, Brian M. Stoltz, and Scott C. Virgil.
Adv. Synth. Catal. 2019, 361, 441–444. [Supporting Information].
"Intramolecular Hydrogen Shift Chemistry of Hydroperoxy-Substituted Peroxy Radicals"
Eric Praske, Rasmus V. Otkjaer, John D. Crounse, J. Caleb Hethcox, Brian M. Stoltz, Henrik G. Kjaergaard, and Paul O. Wennberg.
J. Phys. Chem. A 2019, 123, 590–600. [Supporting Information].
"Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis"
Eric R. Welin, Aurapat Ngamnithiporn, Max Klatte, Guillaume Lapointe,
Gerit M. Pototschnig, Martina S. J. McDermott, Dylan Conklin, Christopher D. Gilmore,
Pamela M. Tadross, Christopher K. Haley, Kenji Negoro, Emil Glibstrup,
Christian U. Grünanger, Kevin M. Allan, Scott C. Virgil, Dennis J. Slamon,
and Brian M. Stoltz.
Science 2019, 363, 270–275. [Supporting Information].
"Concise Syntheses of Δ12-Prostaglandin J Natural Products via Stereoretentive Metathesis"
Jiaming Li, Tonia S. Ahmed, Chen Xu, Brian M. Stoltz, and Robert H. Grubbs.
J. Am. Chem. Soc. 2018, ASAP [Supporting Information].
"Discussion Addendum for: Preparation of (S)-tert-ButylPHOX and (S)-2-Allyl-2-Methylcyclohexanone"
Alexander W. Sun and Brian M. Stoltz.
Org. Synth. 2018, 95, 439–454.
"The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination"
Christopher G. Jones†, Michael W. Martynowycz†, Johan Hattne, Tyler J. Fulton, Brian M. Stoltz, Jose A. Rodriguez, Hosea M. Nelson, and Tamir Gonen.
ACS Cent. Sci. 2018, 4, 1587–1592. †Equal Contribution. [Supporting Information]. ChemRXiv Preprint. Caltech Feature Story
"Enantioselective Synthesis of gem-Disubstituted N-Boc Diazaheterocycles via Decarboxylative Asymmetric Allylic Alkylation"
Alexander W. Sun†, Stephan N. Hess† and Brian M. Stoltz.
Chem. Sci. 2018, 10, 788–792. †Equal Contribution. [Supporting Information].
"Catalyst-Controlled Selective Functionalization of Unactivated C–H Bonds in the Presence of Electronically Activated C–H Bonds"
Wenbin Liu, Zhi Ren, Aaron T. Bosse, Kuangbiao Liao, Elizabeth L. Goldstein, John Bacsa, Djamaladdin G. Musaev, Brian M. Stoltz, and Huw M. L. Davies.
J. Am. Chem. Soc. 2018, 140, 12247–12255. [Supporting Information].
"Palladium-Catalyzed Enantioselective Csp3–Csp3 Cross-Coupling for the Synthesis of (Poly)fluorinated Chiral Building Blocks"
Yanhui Lu, Elizabeth L. Goldstein, and Brian M. Stoltz.
Org. Lett. 2018, 20, 5657–5660. [Supporting Information].
"Synergistic O3 + OH oxidation pathway to extremely low-volatility dimers revealed in β-pinene secondary organic aerosol"
Christopher M. Kenseth, Yuanlong Huang, Ran Zhao, Nathan F. Dalleska, J. Caleb Hethcox, Brian M. Stoltz, and John H. Seinfeld.
Proc. Natl. Acad. Sci. U S A 2018, 115, 8301–8306. [Supporting Information].
"Intermolecular Stereoselective Iridium-Catalyzed Allylic Alkylation: An Evolutionary Account"
Samantha E. Shockley, J. Caleb Hethcox, and Brian M. Stoltz.
Synlett 2018, 29, A–L.
"General and Practical KOMe/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides"
Xin Wang, Ming-Hui Zhu, David P Schuman, Dayou Zhong, Wen-Yan Wang, Lin-Yang Wu, Wei Liu, Brian M. Stoltz, and Wen-Bo Liu.
J. Am. Chem. Soc. 2018, 140,10970–10974 [Supporting Information].
"Catalytic Enantioselective Synthesis of Acyclic Quaternary Centers: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Acyclic Enol Carbonates"
Eric J. Alexy, Haiming Zhang, and Brian M. Stoltz.
J. Am. Chem. Soc. 2018, 140, 10109–10112. [Supporting Information]. This article was featured in Synfacts!
"Short Enantioselective Formal Synthesis of (–)-Platencin"
Christian Defieber, Justin T. Mohr , Gennadii A. Grabovyi, Brian M. Stoltz.
Synthesis 2018, 50, A–J [Supporting Information].
"Total Synthesis of the Norhasubanan Alkaloid Stephadiamine"
Nina Hartrampf, Nils Winter, Gabriele Pupo, Brian M. Stoltz, and Dirk Trauner.
J. Am. Chem. Soc. 2018, 140, 8675–8680. [Supporting Information]. This article was featured in Synfacts!
"Enantioselective Synthesis of Vicinal All-Carbon Quaternary Centers via Iridium-Catalyzed Allylic Alkylation"
J. Caleb Hethcox, Samantha E. Shockley, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2018, 57, 1–5. [Supporting Information]. This article was featured in Synfacts!
"Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids"
Beau P. Pritchett and Brian M. Stoltz.
Nat. Prod. Rep. 2018, 35, 559-574.
"Development of a Unified Enantioselective, Convergent Synthetic Approach Toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Asymmetric Formation of the Polycyclic Norditerpenoid Carbocyclic Core by Tandem Annulation Cascade"
Robert A. Craig, II, Russell C. Smith, Jennifer L. Roizen, Amanda C. Jones, Scott C. Virgil, and Brian M. Stoltz.
J. Org. Chem. 2018, 83, 3467–3485. [Supporting Information].
"Nickel-Catalyzed Enantioselective Allylic Alkylation of Lactones and Lactams with Unactivated Allylic Alcohols"
Fa Ngamnithiporn, Carina Jette, Shoshana Bachman, Scott Virgil, and Brian M. Stoltz.
Chemical Science 2018, 9, 2547-2551. [Supporting Information].
"The Cyanthiwigin Natural Product Core as a Complex Molecular Scaffold for Comparative Late-Stage C–H Functionalization Studies"
Kelly E. Kim, Ashley M. Adams, Nicholas D. Chiappini, J. Du Bois, and Brian M. Stoltz
J. Org. Chem. 2018, 83, 3023–3033. [Supporting Information]. This article was featured on the March 16, 2018 cover of JOC! It was also an Editor's Choice article!
"Wolff/Cope Approach to the AB Ring of the Sesterterpenoid Variecolin"
Michael R Krout, Christopher Edwin Henry, Thomas Jensen, Kun-Liang (Phil) Wu, Scott C Virgil, and Brian M. Stoltz
J. Org. Chem. 2018, 83, 6995–7009. [Supporting Information].
"Atmospheric autoxidation is increasingly important in urban and suburban North America"
Eric Praske, Rasmus V. Otkjær, John D. Crounse, J. Caleb Hethcox, Brian M. Stoltz, Henrik G. Kjaergaard, and Paul O. Wennberg.
PNAS 2017, 115, 64-69. [Supporting Information].
"Isocanthine Synthesis via Rh(III)-Catalyzed Intramolecular C–H Functionalization"
Anthony Y. Chen, Qianqian Lu, Yao Fu, Richmond Sarpong, Brian M. Stoltz, and Haiming Zhang.
JOC 2017, 83, 330–337. [Supporting Information].
"Model Studies To Access the [6,7,5,5]-Core of Ineleganolide Using Tandem Trans lactonization Cope or Cyclopropanation Cope Rearrangements as Key Steps"
Jennifer L. Roizen, Amanda C. Jones, Russell C. Smith, Scott C. Virgil, and Brian M. Stoltz.
JOC 2017, 82, 13051–13067. [Supporting Information].
"Catalytic Reduction of Alkyl and Aryl Bromides using Isopropanol"
Michael C. Haibach, Brian M. Stoltz, and Robert H. Grubbs.
ACIE 2017, 56, 15123–15126 . [Supporting Information].
"Sequential Ruthenium Catalysis for Olefin Isomerization and Oxidation: Application to the Synthesis of Unusual Amino Acids"
Marc Liniger, Yiyang Liu, and Brian M. Stoltz.
JACS 2017, 139, 13944–13949. [Supporting Information].
"Enantioselective Pd-Catalyzed Decarboxylative Allylic Alkylation of Thiopyranones. Access to Acyclic, Stereogenic α-Quaternary Ketones"
Eric J. Alexy, Scott C. Virgil, Michael D. Bartberger, and Brian M. Stoltz.
Org. Lett. 2017, 19, 5007–5009. [Supporting Information].
"Progress towards the total synthesis of hamigerans C and D: a direct approach to an elaborated 6-7-5 carbocyclic core"
Doug C. Duquette, Thomas Jensen, and Brian M. Stoltz.
J. Antibiot. 2017, 71, 263–267. [Supporting Information].
"Enantioselective Catalysis Coupled with Stereodivergent Cyclization Strategies Enables Rapid Syntheses of (+)-Limaspermidine and (+)-Kopsihainanine A"
Beau P. Pritchett,† Etienne J. Donckele,† Brian M. Stoltz
ACIE 2017, 56, 12624 –12627. [Supporting Information]. †Equal Contribution.
"Enantioselective Synthesis of Acyclic α-Quaternary Carboxylic Acid Derivatives via Iridium-Catalyzed Allylic Alkylation"
Samantha Shockley,† John Caleb Hethcox† and Brian Stoltz.
ACIE 2017, 56, 10196–10199. [Supporting Information]. †Equal Contribution. Check out the Synfacts highlight!
"Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme"
Steven A. Loskot, David K. Romney, Frances H. Arnold, and Brian M. Stoltz
J. Am. Chem. Soc. 2017, 139, 10196–10199. [Supporting Information].
"Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Amide Enolates"
Pavel Starkov,† Jared T. Moore,† Douglas C. Duquette, Brian M. Stoltz, and Ilan Marek.
J. Am. Chem. Soc. 2017, 139, 9615–9620. [Supporting Information]. †Equal Contribution.
"Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy"
Samantha E. Shockley,† J. Caleb Hethcox,† and Brian M. Stoltz.
Tetrahedron Lett. 2017, 58, 3341-3343. [Supporting Information]. †Equal Contribution.
"Polycyclic Furanobutenolide-Derived Cembranoid and Norcembranoid Natural Products: Biosynthetic Connections and Synthetic Efforts"
Robert A. Craig II and Brian M. Stoltz.
Chem. Rev. 2017, 117, 7878–7909.
"Ionic and Neutral Mechanisms for C–H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium tert-Butoxide"
Shibdas Banerjee,† Yun-Fang Yang,† Ian D. Jenkins,† Yong Liang, Anton A. Toutov, Wen-Bo Liu,
David P. Schuman, Robert H. Grubbs, Brian M. Stoltz, Elizabeth H. Krenske,
Kendall N. Houk, and Richard N. Zare.
J. Am. Chem. Soc. 2017, 139, 6880. [Supporting Information]. †Equal Contribution.
"Potassium tert-Butoxide-Catalyzed Dehydrogenative C−H Silylation
of Heteroaromatics: A Combined Experimental and Computational
Mechanistic Study"
Wen-Bo Liu,† David P. Schuman,† Yun-Fang Yang,† Anton A. Toutov, Yong Liang,
Hendrik F. T. Klare, Nasri Nesnas, Martin Oestreich, Donna G. Blackmond, Scott C. Virgil,
Shibdas Banerjee, Richard N. Zare, Robert H. Grubbs, K. N. Houk, and Brian M. Stoltz.
J. Am. Chem. Soc. 2017, 139, 6867. [Supporting Information]. †Equal Contribution.
"Enantioselective Iridium-Catalyzed Allylic Alkylation Reactions of Masked Acyl Cyanide Equivalents"
J. Caleb Hethcox,† Samantha E. Shockley,† and Brian M. Stoltz.
Org. Lett. 2017, 19, 1527. [Supporting Information]. †Equal Contribution.
"A Fischer Indolization Strategy toward the Total Synthesis of (–)-Goniomitine"
Beau P. Pritchett, Jun Kikuchi, Yoshitaka Numajiri, and Brian M. Stoltz.
Heterocycles 2017, 95, 1245-1253. [Supporting Information].
"Oxidative Fragmentations and Skeletal Rearrangements of Oxindole Derivatives"
Hendrik F. T. Klare, Alexander F. G. Goldberg, Douglas C. Duquette, and Brian M. Stoltz*
Org. Lett. 2017, 19, 988. [Supporting Information].
"Advances in Stereoconvergent Catalysis from 2005 to 2015: Transition-Metal-Mediated Stereoablative Reactions, Dynamic Kinetic Resolutions, and Dynamic Kinetic Asymmetric Transformations"
Vikram Bhat, Eric R. Welin, Xuelei Guo, and Brian M. Stoltz.
Chem. Rev. 2017, 117, 4528.
"Alkali metal hydroxide–catalyzed C(sp)–H bond silylation"
Anton Toutov,† Kerry Betz,† David Phillip Schuman, Wen-bo Liu, Alexey Fedorov, Brian M. Stoltz, and Robert H. Grubbs.
J. Am. Chem. Soc. 2017, 139, 1668. [Supporting Information]. †Equal Contribution.
"Single-step synthesis of 3-hydroxycarbazoles by annulation of electron-rich anilines and quinones"
Eugenia Pushkarskaya, Brian Wong, Chong Han, Simona Capomolla, Chunang Gu, Brian M. Stoltz, Haiming Zhang.
Tetrahedron Lett. 2016, 57, 5653. [Supporting Information].
"Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride"
J. Caleb Hethcox,† Samantha E. Shockley,† and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2016, 55, 16092. [Supporting Information]. †Equal Contribution. Check out the Synfacts highlight!
"A Second-Generation Synthesis of the Cyanthiwigin Natural Product Core"
Kelly E. Kim and Brian M. Stoltz.
Org. Lett. 2016, 18, 5720. [Supporting Information]
"Palladium-Catalyzed Aerobic Intramolecular Aminoacetoxylation of Alkenes Enabled by Catalytic Nitrate"
Jiaming Li, Robert H. Grubbs, and Brian M. Stoltz.
Org. Lett. 2016, 18, 5449. [Supporting Information]
"Catalytic Anti-Markovnikov Transformations of Hindered Terminal Alkenes Enabled by Aldehyde-Selective Wacker-Type Oxidation"
Kelly E. Kim, Jiaming Li, Robert H. Grubbs, and Brian M. Stoltz.
J. Am. Chem. Soc. 2016, 138, 13179. [Supporting Information]
"Enantioselective Pd-Catalyzed Allylic Alkylation Reactions of Dihydropyrido[1,2-a]indolone Substrates: Efficient Syntheses of (−)-Goniomitine, (+)-Aspidospermidine, and (−)-Quebrachamine"
Beau P. Pritchett, Jun Kikuchi, Yoshitaka Numajiri, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2016, 55, 13529. [Supporting Information]
"Enantioconvergent catalysis"
Justin T. Mohr, Jared T. Moore, and Brian M. Stoltz.
Beilstein J. Org. Chem. 2016, 12, 2038.
"Potassium tert-Butoxide–Catalyzed Dehydrogenative Cross-Coupling
of Heteroarenes with Hydrosilanes"
Anton A. Toutov, Wen-Bo Liu, Brian M. Stoltz and Robert H. Grubbs.
Org. Synth., 2016, 93, 263.
"Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates"
J. Caleb Hethcox,† Samantha E. Shockley,† and Brian M. Stoltz.
ACS Catal., 2016, 6, 6207. †Equal Contribution.
"Enantioselective, Convergent Synthesis of the Ineleganolide Core by a Tandem Annulation Cascade"
Robert A. Craig, II, Jennifer L. Roizen, Russell Smith, Amanda C. Jones, Scott Virgil and Brian M. Stoltz.
Chem. Sci, 2017, 8, 507. [Supporting Information]
"Escherichia coli K1 modulates peroxisome proliferator-activated receptor-gamma and glucose transporter-1 at the blood-brain barrier in neonatal meningitis"
Subramanian Krishnan, Alexander C. Chang, Brian M. Stoltz, and Nemani V. Prasadarao.
J. Infect. Dis., 2016, 214, 1092. This article was featured in a press release from Children's Hospital, Los Angeles
"Preparation of 1,5-Dioxaspiro[5.5]undecan-3-one"
Robert A. Craig, II, Russell C. Smith, Beau P. Pritchett, Benzi I. Estipona, and Brian M. Stoltz.
Org. Synth., 2016, 93, 210.
"Ni-Catalyzed Enantioselective C-Acylation of α-Substituted Lactams"
Masaki Hayashi, Shoshana Bachman, Satoshi Hashimoto, Chad C. Eichman, and Brian M. Stoltz.
J. Am. Chem. Soc. 2016, 138, 8997.
[Supporting Information]. Check out the Synfacts highlight.
"Synthesis of Aryl Ketoamides via Aryne Insertion into Imides"
Austin C. Wright, Christopher K. Haley, Guillaume Lapointe, and Brian M. Stoltz.
Org. Lett. 2016, 18, 2793.
[Supporting Information]
"Nickel-Catalyzed Intramolecular C−O Bond Formation: Synthesis of Cyclic Enol Ethers"
Seo-Jung Han, Ryohei Doi, Brian M. Stoltz.
Angew. Chem. Int. Ed. 2016, 55, 7437.
[Supporting Information]
"A mild and efficient approach to enantioenriched α-hydroxyethyl α,β-unsaturated Δ-lactams"
Seo-Jung Han, Brian M. Stoltz.
Tetrahedron Lett. 2016, 57, 2233.
[Supporting Information]
"Enantioselective Synthesis of Caprolactam and Enone Precursors to the Heterocyclic DEFG Ring System of Zoanthenol"
Jeffrey T. Bagdanoff, Douglas C. Behenna, Jennifer L. Stockdill, and Brian M. Stoltz.
Eur. J. Org. Chem. 2016, 2016, 2101.
[Supporting Information]
"Enantioselective γ-Alkylation of α,β-Unsaturated Malonates and Ketoesters by a Sequential Ir-Catalyzed Asymmetric Allylic Alkylation/Cope Rearrangement"
Wen-Bo Liu,† Noriko Okamoto,† Eric J. Alexy, Allen Y. Hong, Kristy Tran, and Brian M. Stoltz.
J. Am. Chem. Soc. 2016, 138, 5234. †Equal Contribution.
[Supporting Information]. Check out the Synfacts highlight!
"Catalytic enantioselective total synthesis of (+)-eucomic acid"
Benzi I. Estipona,† Beau P. Pritchett, Robert A. Craig II, Brian M. Stoltz.
Tetrahedron, 2016, 72, 3707. †Caltech Undergrad.
[Supporting Information]
"Synthetic Applications and Methodological Developments of Donor-Acceptor Cyclopropanes and Related Compounds"
Nicholas R. O’Connor, John L. Wood, Brian M. Stoltz.
Isr. J. Chem., 2016, 56, 431.
"Development of a simple system for the oxidation of electron-rich diazo compounds to ketones"
Nicholas R. O’Connor, Peter Bolgar, Brian M. Stoltz.
Tetrahedron Lett., 2016, 57, 849. [Supporting Information]
"Total Synthesis and Characterization of 7-Hypoquinuclidonium Tetrafluoroborate and 7-Hypoquinuclidone BF3 Complex"
Marc Liniger, David G. VanderVelde, Michael K. Takase, Mona Shahgholi, Brian M. Stoltz.
J. Am. Chem. Soc., 2016, 138, 969.
"Catalytic C–H bond silylation of aromatic heterocycles"
Anton A Toutov,† Wen-Bo Liu,† Kerry N. Betz, Brian M. Stoltz. Robert H. Grubbs.
Nat. Protoc., 2015, 10, 1897. †Equal Contribution.
"Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Cyclopentanones"
Robert A. Craig II,† Steven A. Loskot,† Justin T. Mohr, Douglas C. Behenna, Andrew M. Harned, Brian M. Stoltz.
Org. Lett., 2015, 17, 5160. †Equal Contribution. [Supporting Information]. This article was featured in Synfacts!
"Label-free detection of single nanoparticles and biological molecules using microtoroid optical resonators"
Judith Su, Alexander F.G. Goldberg, Brian M. Stoltz.
Light Sci. Appl., 2016, 5, e16001.
"Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids"
Jeffrey C. Holder, Samantha E. Shockley, Mario P. Wiesenfeldt, Hideki Shimizu, Brian M. Stoltz.
Org. Synth., 2015, 92, 247.
"Palladium(II)-Catalyzed Allylic C-H Oxidation of Hindered Substrates Featuring Tunable Selectivity Over Extent of Oxidation"
Xiangyou Xing,† Nicholas R. O'Connor,† Brian M. Stoltz.
Angew. Chem. Int. Ed., 2015, 54, 11186. †Equal Contribution.
[Supporting Information]
"Palladium-Catalyzed Decarbonylative Dehydration for the Synthesis of α-Vinyl Carbonyl Compounds and Total Synthesis of (−)-Aspewentins A, B, and C"
Yiyang Liu, Scott C. Virgil, Robert H. Grubbs, Brian M. Stoltz.
Angew. Chem. Int. Ed., 2015, 54, 11800.
[Supporting Information]
"Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles"
Samantha E. Shockley, Jeffrey C. Holder, Brian M. Stoltz.
Org. Process Res. Dev., 2015, 19, 974.
"An Efficient Protocol for the Palladium-Catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst"
Alexander N. Marziale, Douglas C. Duquette, Robert A. Craig II, Kelly E. Kim, Marc Liniger, Yoshitaka Numajiri, Brian M. Stoltz.
Adv. Synth. Catal. 2015, 357, 2238.
[Supporting Information]
"Synthesis and Exploration of Electronically Modified (R)-5,5-Dimethyl-(p-CF3)3-i-PrPHOX in Palladium-Catalyzed Enantio- and Diastereoselective Allylic Alkylation: A Practical Alternative to (R)-(p-CF3)3-t-BuPHOX"
Robert A. Craig II, Brian M. Stoltz.
Tetrahedron Lett. 2015, 56, 4670.
[Supporting Information]
"Construction of Tertiary Chiral Centers by Pd-catalyzed Asymmetric Allylic Alkylation of Prochiral Enolate Equivalents"
Yusuke Kita, Yoshitaka Numajiri, Noriko Okamoto, Brian M. Stoltz.
Tetrahedron 2015, 71, 6349.
[Supporting Information]
"Exceedingly Efficient Synthesis of (±)-Grandifloracin and Acylated Analogues"
Magnus Bergner, Douglas C. Duquette, Linda Chio, Brian M. Stoltz.
Org. Lett. 2015, 17, 3008.
[Supporting Information]
"Enantioselective Synthesis of Dialkylated N-Heterocycles by Palladium-Catalyzed Allylic Alkylation"
Yoshitaka Numajiri, Gonzalo Jiménez-Osés, Bo Wang, Ken N. Houk, Brian M. Stoltz.
Org. Lett. 2015, 17, 1082.
[Supporting Information]
"Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules"
Yiyang Liu, Seo-Jung Han, Wen-Bo Liu, and Brian M. Stoltz.
Acc. Chem. Res. 2015, 48, 740. Please also see Prof. Paul Wender's accompanying editorial, entitled "Art, Architecture, and the Molecular Frontier."
"Silylation of C–H bonds in Aromatic Heterocycles by an Earth-abundant Metal Catalyst"
Anton A. Toutov,† Wen-Bo Liu,† Kerry N. Betz, Alexey Fedorov, Brian M. Stoltz, Robert H. Grubbs.
Nature 2015, 518, 80. †Equal Contribution.
[Supporting Information]. This article was featured in Synfacts!
"Selective Syntheses of Leuconolam, Leuconoxine, and Mersicarpine Alkaloids from a Common Intermediate through Regiocontrolled Cyclizations by Staudinger Reactions"
Zining Li, Qian Geng, Zhe Lv, Beau P. Pritchett, Katsuaki Baba, Yoshitaka Numajiri, Brian M. Stoltz, Guangxin Liang.
Org. Chem. Front. 2015, 2, 236.
[Supporting Information]
"Enantioselective Synthesis of α-Quaternary Mannich Adducts by Palladium-Catalyzed Allylic Alkylation: Total Synthesis of (+)-Sibirinine"
Yoshitaka Numajiri, Beau P. Pritchett, Koji Chiyoda, Brian M. Stoltz.
J. Am. Chem. Soc. 2015, 137, 1040.
[Supporting Information] This article was featured in Synfacts!
"Mechanistic Analysis of an Asymmetric Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β-Substituted Cyclic Enones"
Cornelia L. Boeser, Jeffrey C. Holder, Buck L. H. Taylor, K. N. Houk, Brian M. Stoltz, Richard N. Zare.
Chem. Sci. 2015, 6, 1917.
[Supporting Information]
"Synthesis of Diverse β-Quaternary Ketones via Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Cyclic Enones"
Jeffrey C. Holder, Emmett D. Goodman, Kotaro Kikushima, Michele Gatti, Alexander N. Marziale, Brian M. Stoltz.
Tetrahedron 2015, 71, 5781.
"Evolution of a Unified, Stereodivergent Approach to the Synthesis of Communesin F and Perophoramidine"
Seo-Jung Han, Florian Vogt, Jeremy A. May, Shyam Krishnan, Michele Gatti, Scott C. Virgil, Brian M. Stoltz.
J. Org Chem. 2015, 80, 528.
[Supporting Information]
"Enantioselective Synthesis of α-Secondary and α-Tertiary Piperazin-2-ones and Piperazines by Catalytic Asymmetric Allylic Alkylation"
Katerina M. Korch, Christian Eidamshaus, Douglas C. Behenna, Sangkil Nam, David Horne, Brian M. Stoltz.
Angew. Chem. Int. Ed. 2015, 54, 179. Also in press here.
[Supporting Information]
"A Catalytic, Enantioselective Formal Synthesis of (+)-Dichroanone and (+)-Taiwaniaquinone H"
Samantha E. Shockley, Jeffrey C. Holder, Brian M. Stoltz.
Org. Lett. 2014, 16, 6362.
[Supporting Information]
"Stereochemical evaluation of bis(phosphine) copper catalysts for the asymmetric alkylation of 3-bromooxindoles with α-arylated malonate esters"
Chung Whan Lee, Seo-Jung Han, Scott C. Virgil, Brian M. Stoltz.
Tetrahedron 2014, 71, 3666.
[Supporting Information]
"Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation"
Yiyang Liu, Marc Liniger, Ryan M. McFadden, Jenny L. Roizen, Jacquie Malette, Corey M. Reeves, Douglas C. Behenna, Masaki Seto, Jimin Kim, Justin T. Mohr, Scott C. Virgil and Brian M. Stoltz.
Beilstein J. Org. Chem. 2014, 10, 2501.
[Supporting Information]
"The Total Syntheses of Basiliolide C, epi-Basiliolide C, and Protecting-Group-Free Total Syntheses of Transtaganolides C and D"
Jonny R. Gordon, Hosea M. Nelson, Scott C. Virgil, Brian M. Stoltz.
J. Org. Chem. 2014, 79. 9740.
[Supporting Information]
"A New Method for the Cleavage of Nitrobenzyl Amides and Ethers"
Seo-Jung Han, Gabriel Fernando de Melo, Brian M. Stoltz.
Tet. Lett. 2014, 55, 6467.
"Highly functionalized donor–acceptor cyclopropanes applied toward the synthesis of the Melodinus alkaloids"
Alexander F.G. Goldberg,
Robert A. Craig II,† Nicholas R. O’Connor,† Brian M. Stoltz.
Tet. Lett. 2014, 56, 2983.
†Equal Contribution
"A Diastereodivergent Synthetic Strategy for the Syntheses of Communesin F and Perophoramidine"
Seo-Jung Han, Florian Vogt, Shyam Krishnan, Jeremy A. May, Michele Gatti, Scott C. Virgil, Brian M. Stoltz.
Org. Lett. 2014, 16, 3316.
[Supporting Information]
"Biosynthesis and Chemical Synthesis of Presilphiperfolanol Natural Products"
Allen Y. Hong, Prof. Brian M. Stoltz.
Angew. Chem. Int. Ed. 2014, 53, 5248. Also in press here.
"Development of (Trimethylsilyl)ethyl Ester Protected Enolates and Applications in Palladium-Catalyzed Enantioselective Allylic Alkylation: Intermolecular Cross-Coupling of Functionalized Electrophiles"
Corey M. Reeves, Douglas C. Behenna, Prof. Brian M. Stoltz.
Org. Lett. 2014, 16, 2314.
[Supporting Information]
"Palladium-catalyzed decarboxylative allylic alkylation of diastereomeric β-ketoesters"
Sandy Ma, Corey M. Reeves, Robert A. Craig II, Prof. Brian M. Stoltz.
Tetrahedron 2014, 70, 4208.
[Supporting Information]
"Stereoselective Lewis Acid Mediated (3+2) Cycloadditions of N-H- and N-Sulfonylaziridines with Heterocumulenes"
Robert A. Craig II, Nicholas R. O'Connor, Dr. Alexander F. G. Goldberg, Prof. Brian M. Stoltz.
Chem. – Eur. J. 2014, 20. 4806.
[Supporting Information]
"Toward a Symphony of Reactivity: Cascades Involving Catalysis and Sigmatropic Rearrangements"
Amanda Jones, Brian M. Stoltz*, Jeremy A. May, Richmond Sarpong.
Angew. Chem. Int. Ed. 2014, 53, 2556. Also in press at
Angew. Chem. 2014 126, 2590.
"Gas Phase Production and Loss of Isoprene Epoxydiols"
Kelvin H. Bates, John D. Crounse, Jason M. St. Clair, Nathan B. Bennett, Tran B. Nguyen, John H. Seinfeld, Brian M. Stoltz, and Paul O. Wennberg.
J. Phys. Chem. A 2014, 118, 1237.
[Supporting Information]
"Palladium-Catalyzed Decarbonylative Dehydration of Fatty Acids for the Production of Linear Alpha Olefins"
Yiyang Liu, Kelly E. Kim, Myles B. Herbert, Alexey Fedorov, Robert H. Grubbs, Brian M. Stoltz.
Adv. Synth. Catal. 2014, 356, 130.
[Supporting Information].
Additionally, this article was featured on the organic-chemistry.org webportal, which can be accessed here.
"A Unified Approach to the Daucane and Sphenolobane Bicyclo[5.3.0]decane Core: Enantioselective Total Syntheses of Daucene, Daucenal, Epoxydaucenal B, and 14-para-Anisoyloxydauc-4,8-diene"
Nathan B. Bennett, and Brian M. Stoltz.
Chem. – Eur. J. 2013, 52, 17745.
[Supporting Information]
"Enantio-, Diastereo- and Regioselective Iridium-Catalyzed Asymmetric Allylic Alkylation of Acyclic β-Ketoesters"
Wen-Bo Liu, Corey M. Reeves, and Brian M. Stoltz.
J. Am. Chem. Soc. 2013, 135, 17298.
[Supporting Information]This article was Synfact of the Month!
"Asymmetric Synthesis of QUINAP via Dynamic Kinetic Resolution"
Vikram Bhat, Su Wang, Brian M. Stoltz, and Scott C Virgil.
J. Am. Chem. Soc. 2013, 135, 16829.
[Supporting Information]This article was featured in Synfacts!
"Angiotensin receptor I - A novel target for preventing neonatal meningitis in mice by Escherichia coli K1"
Subramanian Krishnan, Muthusamy V. Shanmuganathan, Douglas Behenna, Brian M. Stoltz and Nemani V. Prasadarao.
J. Infect. Dis. 2013, 209, 409.
[Supporting Information]
"Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β-Substituted Cyclic Enones: Insights from Computation and Experiment"
Jeffrey C. Holder, Lufeng Zou, Alexander N. Marziale, Peng Liu, Yu Lan, Michele Gatti, Kotaro Kikushima, K. N. Houk, and Brian M. Stoltz.
J. Am. Chem. Soc. 2013, 135, 14996.
[Supporting Information]
"A scalable synthesis of the (S)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole ((S)-t-BuPyOx) ligand"
Hideki Shimizu, Jeffrey C. Holder and Brian M. Stoltz.
Beilstein J. Org. Chem. 2013, 9, 1637.
[Supporting Information]
"Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters via Ir-Catalyzed Regio‑, Diastereo‑, and Enantioselective Allylic Alkylation and Applications in Sequential Pd Catalysis"
Wen-Bo Liu, Corey M. Reeves, Scott C. Virgil, and Brian M. Stoltz.
J. Am. Chem. Soc. 2013, 135, 10626.
[Supporting Information] This article was featured in Synfacts!
"Enantioselective Synthesis of the 5–6–7 Carbocyclic Core of the Gagunin Diterpenoids"
Grant M. Shibuya , John A. Enquist , Jr., and Brian M. Stoltz.
Org. Lett. 2013, 15, 3480.
[Supporting Information]
"Selective Nucleic Acid Capture with Shielded Covalent Probes"
Jeffrey R. Vieregg, Hosea M. Nelson, Brian M. Stoltz, and Niles A. Pierce.
J. Am. Chem. Soc. 2013, 135, 9691.
[Supporting Information]
"Enantioselective Construction of α-Quaternary Cyclobutanones by Catalytic Asymmetric Allylic Alkylation"
Corey M. Reeves, Christian Eidamshaus, Jimin Kim, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2013, 52, 6718.
[Supporting Information] This article was featured in Synfacts!
"Total Syntheses of (−)-Transtaganolide A, (+)-Transtaganolide B, (+)-Transtaganolide C, and (−)-Transtaganolide D and Biosynthetic Implications"
Hosea M. Nelson, Jonny R. Gordon, Scott C. Virgil, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2013, 52, 6699.
[Supporting Information]
"The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis"
Allen Y. Hong and Brian M. Stoltz.
Eur. J. Org. Chem. 2013, 14, 2745.
"Development of a palladium-catalyzed decarboxylative cross-coupling of (2-azaaryl)carboxylates with aryl halides"
Christopher K. Haley, Christopher D. Gilmore, and Brian M. Stoltz.
Tetrahedron. 2013, 69, 5732.
"Expanding Insight into Asymmetric Palladium-Catalyzed Allylic Alkylation of N-Heterocyclic Molecules and Cyclic Ketones"
Nathan B. Bennett,† Douglas C. Duquette,† Jimin Kim, Wen-Bo Liu, Alexander N. Marziale, Douglas C. Behenna, Scott C. Virgil, and Brian M. Stoltz.
Chem. – Eur. J. 2013, 19, 4414.
[Supporting Information]. †Equal Contribution
"Use of a palladium(II)-catalyzed oxidative kinetic resolution in synthetic efforts toward bielschowskysin"
Michael E. Meyer, John H. Phillips, Eric M. Ferreira, and Brian M. Stoltz. Tetrahedron 2013, 69, 7627.
"Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Heterocyclic Acceptors"
Jeffrey C. Holder,† Alexander N. Marziale,† Michele Gatti, Bin Mao, and Brian M. Stoltz. Chem. – Eur. J. 2012, 19, 74.
[Supporting Information]. †Equal Contribution
"Rapid and Convergent Synthesis of a 2,4’-Linked Tri-oxazole in an Approach to Poly-oxazoles"
Daniel D. Caspi, Haiming Zhang, Scott C. Virgil, Fabian M. Piller, and Brian M. Stoltz. Heterocycles. 2012, 86, 1003.
[Supporting Information].
"The Reaction Mechanism of the Enantioselective Tsuji Allylation: Inner-Sphere and Outer-Sphere Pathways, Internal Rearrangements, and Asymmetric C–C Bond Formation"
John A. Keith, Douglas C. Behenna, Nathaniel Sherden, Justin T. Mohr, Sandy Ma, Smaranda C. Marinescu, Robert J. Nielsen, Jonas Oxgaard, Brian M. Stoltz and William A. Goddard, III. J. Am. Chem. Soc. 2012, 134, 19050.
[Supporting Information].
"Enantioselective Synthesis of a Hydroxymethyl-cis-1,3-cyclopentenediol Building Block"
Robert A. Craig, II, Jennifer L. Roizen, Russell C. Smith, Amanda C. Jones, and Brian M. Stoltz. Org. Lett. 2012, 14, 5716.
[Supporting Information].
"Lewis Acid Mediated (3 + 2) Cycloadditions of Donor–Acceptor Cyclopropanes with Heterocumulenes"
Alexander F. G. Goldberg, Nicholas R. O'Connor,† Robert A. Craig, II† and Brian M. Stoltz. Org. Lett. 2012, 14, 5314.
[Supporting Information]. †Equal Contribution
"Enantioselective Total Synthesis of the Reported Structures of (–)-9-epi-Presilphiperfolan-1-ol and (–)-Presilphiperfolan-1-ol: Structural
Confirmation and Reassignment and Biosynthetic Insights."
Allen Y. Hong and Brian M. Stoltz. Angew. Chem. Int. Ed. 2012, 51, 9674.
[Supporting Information]. This article was featured in Synfacts!
"A C–N Insertion of β-Lactam to Benzyne: Unusual Formation of Acridone"
Jimin Kim and Brian M. Stoltz. Tetrahedron Lett. 2012, 53, 4994.
"A Comprehensive History of Arynes in Natural Product Total Synthesis"
Pamela M. Tadross and Brian M. Stoltz. Chem. Rev. 2012, 112, 3550.
"Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams"
Douglas C. Behenna, Yiyang Liu, Taiga Yurino, Jimin Kim, David E. White, Scott C. Virgil and Brian M. Stoltz. Nature Chem. 2012, 4, 130. [Supporting Information]. This article was featured in a press release entitled "Caltech Chemists Devise Chemical Reaction that Holds Promise for New Drug Development".
"Palladium-catalyzed asymmetric alkylation in the synthesis of cyclopentanoid and cycloheptanoid core structures bearing all-carbon quaternary stereocenters"
Allen Y. Hong, Nathan B. Bennett, Michael R. Krout, Thomas Jensen, Andrew M. Harned, Brian M. Stoltz. Tetrahedron 2011, 67, 10234. [Supporting Information].
"Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies"
Douglas C. Behenna, Justin T. Mohr, Nathaniel H. Sherden, Smaranda C. Marinescu, Andrew M. Harned, Kousuke Tani, Masaki Seto, Sandy Ma, Zoltán Novák, Michael R. Krout, Ryan M. McFadden, Jennifer L. Roizen, John A. Enquist Jr., David E. White, Samantha R. Levine, Krastina V. Petrova, Akihiko Iwashita, Scott C. Virgil, Brian M. Stoltz. Chem. – Eur. J. 2011, 17, 14199. [Supporting Information].
"Synthesis of enantioenriched γ-quaternary cycloheptenones using a combined allylic alkylation/Stork–Danheiser approach: preparation of mono-, bi-, and tricyclic systems"
Nathan B. Bennett, Allen Y. Hong, Andrew M. Harned and Brian M. Stoltz. Org. Biomol. Chem. 2012, 10, 56. [Supporting Information]. (This article was one of the top ten downloaded articles for the month of October).
"A Palladium-Catalyzed Vinylcyclopropane (3 + 2) Cycloaddition Approach to the Melodinus Alkaloids"
Alexander F. G. Goldberg and Brian M. Stoltz. Org. Lett. 2011, 13, 4474. (This article was among the top 20 accessed articles for the month of July). [Supporting Information].
"Total Syntheses of Cyanthiwigins B, F, and G"
John A. Enquist Jr., Scott C. Virgil and Brian M. Stoltz. Chem. – Eur. J. 2011, 17, 9957. [Supporting Information].
"A rapid and convergent synthesis of the integrastatin core"
Pamela M. Tadross, Pradeep Bugga and Brian M. Stoltz. Org. Biomol. Chem. 2011, 9, 5354. [Supporting Information]. (This article was selected as an OBC HOT article, and was among the top 10 accessed articles of the month).
"The Catalytic Enantioselective Total Synthesis of (+)-Liphagal"
Joshua J. Day, Ryan M. McFadden, Scott C. Virgil, Helene Kolding, Jennifer L. Alleva, and Brian M. Stoltz. Angew. Chem., Int. Ed. 2011, 50, 6814. [Supporting Information]. This article was featured as a SYNFACT of the month!
"Palladium-Catalyzed, asymmetric Baeyer–Villiger oxidation of prochiral cyclobutanones with PHOX ligands"
Kimberly S. Petersen and Brian M. Stoltz. Tetrahedron 2011, 67, 4352-4357. (This article was highlighted in Org. Process Res. Dev. as an item of interest!)
"Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered
β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters"
Kotaro Kikushima, Jeffrey C. Holder, Michele Gatti, and Brian M. Stoltz. J. Am. Chem. Soc. 2011, 133, 6902. [Supporting Information]. This article was featured as the SYNFACT of the Month!
"Benzannulated Bicycles by Three-Component Aryne Reactions"
Kevin M. Allan, Christopher D. Gilmore, and Brian M. Stoltz. Angew. Chem., Int. Ed. 2011, 50, 4488. [Supporting Information]. This article was featured in an Angew. Chem. Highlight article!
"A General Approach to the Basiliolide/Transtaganolide Natural Products: Total Syntheses of Basiliolide B, epi-8-Basiliolide B, Transtaganolide C, and Transtaganolide D"
Hosea M. Nelson, Kei Murakami, Scott C. Virgil, and Brian M. Stoltz. Angew. Chem., Int. Ed. 2011, 50, 3688. [Supporting Information]. This article was featured in Synfacts!
"Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways" Tsui-Fen Chou, Steve J. Brown, Dmitriy Minond, Brian E. Nordin, Kelin Li, Amanda C. Jones, Peter Chase, Patrick R. Porubsky, Brian M. Stoltz, Frank J. Schoenen, Matthew P. Patricelli, Peter Hodder, Hugh Rosen,
and Raymond J. Deshaies. P. Natl. Acad. Sci. USA 2011, 108, 4834. [Supporting Information]
"Ring-Contraction Strategy for the Practical, Scalable, Catalytic Asymmetric Synthesis of Versatile γ-Quaternary Acylcyclopentenes" Allen Y. Hong, Michael R. Krout, Thomas Jensen, Nathan B. Bennett, Andrew M. Harned, and Brian M. Stoltz. Angew. Chem., Int. Ed. 2011, 50, 2756. [Supporting Information]
"A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B" Herschel Mukherjee, Nolan T. McDougal, Scott C. Virgil, and Brian M. Stoltz. Org Lett. 2011, 13, 825. [Supporting Information]
"Confirmation of the absolute configuration of (–)-aurantioclavine" Douglas C. Behenna, Shyam Krishnan, and Brian M. Stoltz. Tetrahedron Lett. 2010, 52, 2152.[Supporting Information]
"Rapid synthesis of an electron-deficient t-BuPHOX ligand: cross-coupling of aryl bromides with secondary phosphine oxides" Nolan T. McDougal, Jan Streuff, Herschel Mukherjee, Scott C. Virgil and Brian M. Stoltz. Tetrahedron Lett. 2010, 51, 5550.
"High-Throughput Screening of the Asymmetric Decarboxylative Alkylation Reaction of Enolate-Stabilized Enol Carbonates" Nolan T. McDougal, Scott C. Virgil and Brian M. Stoltz. Synlett 2010, 1712.
"A general enantioselective route to the chamigrene natural product family" David E. White, Ian C. Stewart, Brinton A. Seashore-Ludlow, Robert H. Grubbs and Brian M. Stoltz. Tetrahedron 2010, 66, 4668. [Supporting Information]
"Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis" Corinne Baumgartner, Sandy Ma, Qi Liu and Brian M. Stoltz. Org. Biomol. Chem. 2010, 8, 2915. [Supporting Information]
"NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist", Gregory R. Fulmer, Alexander J. M. Miller, Nathaniel H. Sherden, Hugo E. Gottlieb, Abraham Nudelman, Brian M. Stoltz, John E. Bercaw, and Karen I. Goldberg. Organometallics 2010, 29, 2176. [Supporting Information]
"Aryne Acyl-Alkylation in the General and Convergent Synthesis of Benzannulated Macrolactone Natural Products: An Enantioselective Synthesis
of (−)-Curvularin", Pamela M. Tadross, Scott C. Virgil and Brian M. Stoltz. Org. Lett. 2010, 12, 1612. [Supporting Information]
"Regioselective Reactions of Highly Substituted Arynes", Pamela M. Tadross, Christopher D. Gilmore, Pradeep Bugga, Scott C. Virgil, and Brian M. Stoltz.
Org. Lett. 2010, 12, 1224. [Supporting Information]
"A Palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres", Jan Streuff, David E. White, Scott C. Virgil, and Brian M. Stoltz.
Nature Chem. 2010, 2, 192. [Supporting Information]. (This article was also featured in Chem. Eng. News 2010, 88, 30-31 and Synfacts 2010, 6, 685)
"The Palladium-Catalyzed Aerobic Kinetic Resolution of Secondary Alcohols: Reaction Development, Scope, and Applications", David C. Ebner, Jeffrey T. Bagdanoff, Eric M. Ferreira, Ryan M. McFadden, Daniel D. Caspi, Raissa M. Trend, and Brian M. Stoltz.
Chem - Eur J 2009, 15, 12978. [Supporting Information]
"Expedient synthesis of 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones via one-pot aryne acyl-alkylation/condensation", Kevin M. Allan, Boram D. Hong and Brian M. Stoltz.
Org. Biomol. Chem. 2009, 7, 4960. [Supporting Information]
"Catalytic Enantioselective Stereoablative Alkylation of 3-Halooxindoles: Facile Access to Oxindoles with C3 All-Carbon Quaternary Stereocenters", Sandy Ma, Xiaoqing Han, Shyam Krishnan, Scott C. Virgil, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2009, 48, 8037. [Supporting Information]. (This article was also featured in Synfacts, 2010, 65. The article can be found here on the Synfacts page.)
"Unusual Allylpalladium Carboxylate Complexes: Identification of the Resting State of Catalytic Enantioselective Decarboxylative Allylic Alkylation Reactions of Ketones", Nathaniel H. Sherden, Douglas C. Behenna, Scott C. Virgil, and Brian M. Stoltz.
Angew. Chem. Int. Ed. 2009, 48, 6840. [Supporting Information]
"Enantioselective Protonation", Justin T. Mohr, Allen Y. Hong, and Brian M. Stoltz. (This article was featured in the Nature Chemistry first year anniversary highlights).
Nature Chemistry 2009, 1, 359.
"An efficient synthesis of the carbocyclic core of zoanthenol", Jennifer L. Stockdill, Douglas C. Behenna, Andrew McClory, and Brian M. Stoltz.
Tetrahedron 2009, 65, 6571. [Supporting Information]
"Synthetic efforts toward cyathane diterpenoid natural products", John A. Enquist Jr. and Brian M. Stoltz.
Nat. Prod. Rep. 2009, 26, 661.
"Unexpected decarbonylation during an acid-mediated cyclization to access the carbocyclic core of zoanthenol", Jennifer L. Stockdill, Douglas C. Behenna, and Brian M. Stoltz.
Tetrahedron Lett. 2009, 50, 3182. [Supporting Information]
"Preparation of (S)-2-Allyl-2-methylcyclohexanone", Justin T. Mohr, Michael R. Krout, and Brian M. Stoltz.
Org. Synth. 2009, 86, 194.
"Preparation of (S)-tert-ButylPHOX", Michael R. Krout, Justin T. Mohr, and Brian M. Stoltz.
Org. Synth. 2009, 86, 181.
"The Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2-(2-AcetylPhenyl)Acetate.", David C. Ebner, Uttam K. Tambar, and Brian M. Stoltz.
Org. Synth. 2009, 86, 161.
"Progress toward the Synthesis of the Transtaganolide/Basiliolide Natural Products: An Ireland-Claisen Approach", Hosea M. Nelson and Brian M. Stoltz.
Tetrahedron Lett. 2009, 50, 1699.
"Side Chain Chemistry Mediates Backbone Fragmentation in Hydrogen Deficient Peptide Radicals", Qingyu Sun, Hosea Nelson, Tony Ly, Brian M. Stoltz and Ryan R. Julian.
J. Proteome Res. 2009, 8, 958. [Supporting Information]
"Enantioselective Total Synthesis of (+)-Cassiol", Krastina V. Petrova, Justin T. Mohr and Brian M. Stoltz.
Org. Lett. 2009, 11, 293. [Supporting Information]. (This article was also featured in Synfacts, 2009, 719. The article can be found here on the Synfacts page.)
"Catalytic Enantioselective Approach to the Eudesmane Sesquiterpenoids: Total Synthesis of (+)-Carissone", Samantha R. Levine, Michael R. Krout and Brian M. Stoltz.
Org. Lett. 2009, 11, 289. [Supporting Information]
"A Concise Total Synthesis of (-)-Quinocarcin via Aryne Annulation", Kevin M. Allan and Brian M. Stoltz.
J. Am. Chem. Soc. 2008, 130, 17270. [Supporting Information]. (This article was the subject of a Chemistry World Totally Synthetic column, which can be found here.)
"Structural Features and Reactivity of (Sparteine)PdCl2: A Model for Selectivity in the Oxidative Kinetic Resolution of Secondary Alcohols", Raissa M. Trend and Brian M. Stoltz.
J. Am. Chem. Soc. 2008, 130, 15957. [Supporting Information]
"Pd-Catalyzed Enantioselective Aerobic Oxidation of Secondary Alcohols: Applications to the Total Synthesis of Alkaloids", Shyam Krishnan, Jeffrey T. Bagdanoff, David C. Ebner, Yeeman K. Ramtohul, Uttam K. Tambar, and Brian M. Stoltz.
J. Am. Chem. Soc. 2008, 130, 13745. [Supporting Information]
"Natural products as inspiration for the development of asymmetric catalysis", Justin T. Mohr, Michael R. Krout & Brian M. Stoltz.
Nature 2008, 455, 323.
"Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers: Ready Access to C(α)-Tetrasubstituted Hydroxyketones, Acids, and Esters", Masaki Seto, Jennifer L. Roizen, and Brian M. Stoltz. Angew. Chem. Int. Ed.
2008, 47, 6873. [Supporting Information]. (This article was also featured in Synfacts, 2008, 1186. The article can be found here on the Synfacts page.)
"Palladium-Catalyzed Enantioselective Oxidation of Chiral Secondary Alcohols: Access to Both Enantiomeric Series", David C. Ebner, Raissa M. Trend, Cédric Genet,
Matthew J. McGrath, Peter O'Brien, and Brian M. Stoltz. Angew. Chem. Int. Ed.
2008, 47, 6367. [Supporting Information]. (This article was featured in Synfacts, 2009, 121. The article can be found here on the Synfacts page)
"The Total Synthesis of (-)-Cyanthiwigin F by means of Double Catalytic Enantioselective Alkylation", John A. Enquist Jr., Brian M. Stoltz. Nature
2008, 453, 1228. [Supporting Information] (This paper was the topic of a Chemistry World news article that features an
interview with Brian. The article was also the subject of a
"The Biology and Chemistry of the Zoanthamine Alkaloids", Douglas C. Behenna, Jennifer L. Stockdill, Brian M. Stoltz. Angew. Chem. Int.
Ed. 2008, 47, 2365.
"Homogeneous Pd-Catalyzed Enantioselective Decarboxylative Protonation", Smaranda C. Marinescu, Toyoki Nishimata, Justin T. Mohr, and Brian M. Stoltz. Org. Lett. 2008, 10, 1039. [Supporting Information] (This publication was listed as one
of the most accessed communications in Org. Lett. for the January-March 2008 period).
"C–H Bond Functionalizations with Palladium(II): Intramolecular Oxidative Annulations of Arenes", Eric M. Ferreira, Haiming Zhang, and Brian M. Stoltz. Tetrahedron 2008, 64, 5987.
"Orthogonal Synthesis of Indolines and Isoquinolines via Aryne Annulation", Christopher D. Gilmore, Kevin M. Allan, and Brian M. Stoltz. J. Am. Chem. Soc. 2008, 130, 1558. [Supporting Information] (This publication was listed as one
of the most accessed communications in J. Am. Chem. Soc. for the January-March 2008 period).
"The Catalytic Asymmetric Total Synthesis of Elatol", David E. White, Ian C. Stewart, Robert H. Grubbs, and Brian M. Stoltz. J. Am. Chem. Soc. 2008, 130, 810. [Supporting Information]. (This article was also featured in the first issue of JACSβ. This publication was also listed as one
of the most accessed communications in J. Am. Chem. Soc. for the January-March 2008 period).
"Progress toward the Synthesis of the Basiliolides and Transtaganolides: An Intramolecular Pyrone Diels-Alder Entry into a Novel Class of Natural Products", Hosea M. Nelson and Brian M. Stoltz. Org. Lett. 2008, 10, 25. [Supporting Information]
"Enantioselective Tsuji Allylations", Justin T. Mohr and Brian M. Stoltz. Chem. Asian J.
2007, 2, 1476. (This paper has been listed among the most accessed articles
for Chem. Asian J. for the period of August 2007 through July 2008.)
"Catalytic enantioselective stereoablative reactions: an unexploited approach to enantioselective catalysis", Justin T. Mohr, David C. Ebner and Brian M. Stoltz. Org. Biomol. Chem.
2007, 5, 3571. (This paper has
has been listed among the
most accessed papers in Org. Biomol. Chem. for November of 2007.)
"Preparation of 3,3-disubstituted oxindoles by addition of malonates
to 3-halo-oxindoles", Shyam Krishnan and Brian M. Stoltz. Tetrahedron Lett.
2007, 48, 7571.
"The Inner-Sphere Process in the Enantioselective Tsuji
Allylation Reaction with (S)-t-Bu-phosphinooxazoline Ligands",
John A. Keith, Douglas C. Behenna, Justin T. Mohr, Sandy Ma, Smaranda C. Marinescu,
Jonas Oxgaard, Brian M. Stoltz, and William A. Goddard, III. J. Am. Chem. Soc.
2007 129,11876.
[Supporting
Information]
"Convergency and Divergency as Strategic Elements in Total Synthesis:
The Total Synthesis of (-)-Drupacine and the Formal Total Synthesis of (±)-Cephalotaxine,
(-)-Cephalotaxine, and (+)-Cephalotaxine", Qi Liu, Eric M. Ferreira,
and Brian M. Stoltz. J. Org. Chem. 2007 72, 7352.
[Supporting
Information] (This paper has
been listed among the
most accessed papers of J. Org. Chem. for the July-September 2007 period.)
"A Facile and Modular Synthesis of Phosphinooxazoline
Ligands", Kousuke Tani, Douglas C. Behenna, Ryan M. McFadden,
and Brian M. Stoltz. Org. Lett. 2007, 9, 2529.
[Supporting
Information]
"Synthesis of the Carbocyclic Core of
Zoanthenol: Implementation of an Unusual Acid-Catalyzed
Cyclization", Douglas C. Behenna, Jennifer L.
Stockdill, and Brian M. Stoltz. Angew. Chem. Int.
Ed. 2007, 46, 4077.
[Supporting
Information]
"Synthesis of 2-Quinuclidonium by
Eliminating Water: Experimental Quantification of the
High Basicity of Extremely Twisted Amides", Tony Ly,
Michael Krout, Don K. Pham, Kousuke Tani, Brian M.
Stoltz, and Ryan R. Julian. J. Am. Chem. Soc.
2007, 129, 1864. [Supporting
Information]
"Oxidative Kinetic Resolution-Claisen
Rearrangement Sequence to Enantioenriched
Arylcycloalkenes", David C. Ebner, Zoltán
Novák, and Brian M. Stoltz. Synlett
2006, 20, 3533.
"The
development and scope of a versatile tandem
Stille-oxa-electrocyclization reaction", Uttam K.
Tambar, Taichi Kano, John F. Zepernick and Brian M.
Stoltz. Tetrahedron Lett. 2006,
48, 345.
"The
synthesis of C-3β functionalized indoles via a
hydroboration/Suzuki–Miyaura coupling
sequence", Eric M. Ferreira and Brian M. Stoltz.
Tetrahedron Lett. 2006,
47, 8579.
"The Utility of the Classical and
Oxidative Heck Reactions in Natural Product Synthesis:
Studies Directed toward the Total Synthesis of
Dragmacidin F", Neil K. Garg, Daniel D. Caspi, Brian
M. Stoltz. Synlett 2006,
3081.
"Convergent and Diastereoselective
Synthesis of the Polycyclic Pyran Core of Saudin",
Uttam K. Tambar, Taichi Kano, John F. Zepernick, and
Brian M. Stoltz. J. Org. Chem.
2006, 71, 8357. [Supporting Information -
Experimental] [Supporting Information
- Spectra]
"A Convergent and Enantioselective
Synthesis of (+)-Amurensinine via Selective C–H and C–C
Bond Insertion Reactions", Uttam K. Tambar, David C.
Ebner, and Brian M. Stoltz. J. Am. Chem. Soc.
2006, 128, 11752. [Supporting
Information]. (This publication was listed as one
of the
ten most accessed communications in J. Am.
Chem. Soc. for the July-September 2006 period. This
paper was also featured in
Synfacts 2007, 2,
124.)
"Catalytic Enantioselective
Decarboxylative Protonation", Justin T. Mohr, Toyoki
Nishimata, Douglas C. Behenna, and Brian M. Stoltz.
J. Am. Chem. Soc. 2006,
128, 11348. [Supporting
Information]. (This publication has been featured
on the organic-chemistry.org webportal, which can be
accessed
here. This paper was also featured in
Synfacts 2006, 12,
1239.)
"A unified synthetic approach to the
pyrazinone dragmacidins", Neil K. Garg and Brian M.
Stoltz. Chem. Commun. 2006,
3769.
"Synthesis and structural analysis of
2-quinuclidonium tetrafluoroborate", Kousuke Tani and
Brian M. Stoltz. Nature, 2006,
441, 731. [Supporting
Information] (A
forward written by Harry Wasserman was
featured in the "News and Views" section of
Nature, and an article about Brian was featured
in the
"Abstractions" section. This publication was
also featured in
C & E News. This synthesis of
2-quinuclidonium tetrafluoroborate was featured in an
Angew.
Chem. Int. Ed. article by Jonathan Clayden.
Additionally, this synthesis was listed in the
Chemical and Engineering News
Chemistry Highlights of 2006.)
"The Catalytic Enantioselective,
Protecting Group-Free Total Synthesis of
(+)-Dichroanone", Ryan M. McFadden and Brian M.
Stoltz. J. Am. Chem. Soc. 2006,
128, 7738. [Supporting
Information]. (This synthesis was featured as a
"Research Highlight" in Nature.
Additionally, this synthesis was featured in an
Angew. Chem. Int. Ed.
review article focusing on asymmetric
alkylation.)
"The structural and
synthetic implications of the biosynthesis of the
calycanthaceous alkaloids, the communesins, and
nomofungin", Jeremy A. May and Brian M. Stoltz.
Tetrahedron 2006, 62,
5262.
"2-Diazoacetoacetic
acid, an efficient and convenient reagent for the
synthesis of α-diazo-β-ketoesters",
Michael E. Meyer, Eric M. Ferreira, and Brian M. Stoltz.
Chem. Commun. 2006, 1316.
[Supporting
Information]
"Effects of a
Modified Dye-Labeled Nucleotide Spacer Arm on
Incorporation by Thermophilic DNA Polymerases",
Christopher J. Lacenere, Neil K. Garg, Brian M. Stoltz,
and Stephen R. Quake. Nucleosides, Nucleotides &
Nucleic Acids 2006, 25,
9.
"Oxidative Cyclizations in a Nonpolar
Solvent Using Molecular Oxygen and Studies on the
Stereochemistry of Oxypalladation", Raissa M. Trend,
Yeeman K. Ramtohul, and Brian M. Stoltz. J. Am. Chem.
Soc. 2005, 127, 17778.
[Supporting
Information] (This article was listed as a 'Hot
Paper' for National
Chemistry Week 2006.)
"Deracemization of
Quaternary Stereocenters by Pd-Catalyzed
Enantioconvergent Decarboxylative Allylation of Racemic
β-Ketoesters", Justin T. Mohr, Douglas C.
Behenna, Andrew M. Harned and Brian M. Stoltz. Angew.
Chem. Int. Ed. 2005, 44,
6924. [Supporting
Information] (This paper was featured on
organic-chemistry.org, as well as an
Angew. Chem. Int. Ed.
review article focusing on asymmetric
alkylation. This paper was also featured in
Synfacts 2006, 1,
53.)
"A Ligand-Free
Solid-Supported System for Sonogashira Couplings:
Applications in Nucleoside Chemistry", Neil K. Garg,
Carolyn C. Woodroofe, Christopher J. Lacenere, Stephen R.
Quake and Brian M. Stoltz. Chem. Commun.
2005, 4551. [Supporting
Information]
"Heterogeneous
Reductive Isomerization Reaction Using Catalytic Pd/C and
H2", Daniel D. Caspi, Neil K. Garg, and
Brian M. Stoltz. Org. Lett.
2005, 7, 2513. [Supporting
Information]
"Progress Toward
the Total Synthesis of Saudin: Development of a Tandem
Stille-Oxa-Electrocyclization Reaction", Uttam K.
Tambar, Taichi Kano, and Brian M. Stoltz. Org.
Lett. 2005, 7, 2413.
[Supporting
Information]
"Development of an Enantiodivergent
Strategy for the Total Synthesis of (+)- and
(–)-Dragmacidin F from a Single Enantiomer of
Quinic Acid", Neil K. Garg, Daniel D. Caspi, and
Brian M. Stoltz. J. Am. Chem. Soc.
2005, 127, 5970. [Supporting
Information] (This paper was featured in
Synfacts 2005, 2,
184.)
"The Direct Acyl-Alkylation of
Arynes", Uttam K. Tambar and Brian M. Stoltz. J.
Am. Chem. Soc. 2005, 127,
5340. [Supporting
Information] (This paper
was featured in an Angew. Chem. Int. Ed.
highlight on "Aryne Insertions").
"The formal total
synthesis of dragmacidin B, trans-dragmacidin C, and cis-
and trans-dihydrohamacanthins A", Neil K. Garg and
Brian M. Stoltz. Tetrahedron Lett.
2005, 46, 2423.
"Synthesis of
bis(indole)-1,2,4-triazinones", Neil K. Garg and
Brian M. Stoltz. Tetrahedron Lett.
2005, 46, 1997.
"Direct Oxidative
Heck Cyclizations: Intramolecular Fujiwara-Moritani
Arylations for the Synthesis of Functionalized
Benzofurans and Dihydrobenzofurans", Haiming Zhang,
Eric M. Ferreira, and Brian M. Stoltz. Angew. Chem.
Int. Ed. 2004, 43, 6144.
[Supporting
Information]
"The Enantioselective Tsuji
Allylation", Douglas C. Behenna and Brian M. Stoltz.
J. Am. Chem. Soc. 2004,
126, 15044. [Supporting
Information]. (This paper was featured in an
Angew. Chem. Int. Ed.
review article focusing on asymmetric
alkylation.)
"The Total Synthesis of (+)-Dragmacidin
F", Neil K. Garg, Daniel D. Caspi, and Brian M.
Stoltz. J. Am. Chem. Soc. 2004,
126, 9552. [Supporting
Information]
"A Computational Model Relating Structure
and Reactivity in Enantioselective Oxidations of
Secondary Alcohols by (-)-Sparteine-PdII
Complexes", Robert J. Nielsen, Jason M. Keith, Brian
M. Stoltz, and William A. Goddard, III. J. Am. Chem.
Soc. 2004, 126, 7967.
[Supporting
Information]
"Palladium
Catalyzed Aerobic Dehydrogenation: From Alcohols to
Indoles and Asymmetric Catalysis", Brian M.
Stoltz. Chem. Lett. 2004,
33, 362.
"The Resolution of
Important Pharmaceutical Building Blocks by
Palladium-Catalyzed Aerobic Oxidation of Secondary
Alcohols", Daniel D. Caspi, David C. Ebner,
Jeffrey T. Bagdanoff, and Brian M. Stoltz.
Adv. Synth. Catal. 2004,
346, 185. [Supporting
Information]
(This paper is part of a special issue on
oxidation chemistry).
"An Experimentally Derived Model for
Stereoselectivity in the Aerobic Oxidative Kinetic
Resolution of Secondary Alcohols by
(Sparteine)PdCl2", Raissa M. Trend and
Brian M. Stoltz. J. Am. Chem. Soc.
2004, 126, 4482. [Supporting
Information]
"Palladium-Catalyzed Oxidative Kinetic Resolution with
Ambient Air as the Stoichiometric Oxidation Gas",
Jeffrey T. Bagdanoff and Brian M. Stoltz. Angew.
Chem. Int. Ed. 2004, 43,
353. [Supporting
Information]
"Substituent Effects and Nearly
Degenerate Transition States: Rational Design of
Substrates for the Tandem Wolff-Cope Reaction",
Julius T. Su, Richmond Sarpong, Brian M. Stoltz, and
William A. Goddard III. J. Am. Chem. Soc.
2004, 126, 24. [Supporting
Information]
"The Total Synthesis of
(-)-Lemonomycin", Eric R. Ashley, Ernest G. Cruz, and
Brian M. Stoltz. J. Am. Chem. Soc.
2003, 125, 15000. [Supporting
Information]
"The Development of a Facile Tandem
Wolff/Cope Rearrangement for the Synthesis of Fused
Carbocyclic Skeletons", Richmond Sarpong, Julius T.
Su, and Brian M. Stoltz. J. Am. Chem. Soc.
2003, 125, 13624. [Supporting
Information]
"Catalytic C–H Bond Functionalization
with Palladium(II): Aerobic Oxidative Annulations of
Indoles", Eric M. Ferreira, and Brian M. Stoltz.
J. Am. Chem. Soc. 2003,
125, 9578. [Supporting
Information]
"Palladium-Catalyzed Oxidative Wacker Cyclizations in
Nonpolar Organic Solvents with Molecular Oxygen: A
Stepping Stone to Asymmetric Aerobic Cyclizations",
Raissa M. Trend, Yeeman K. Ramtohul, Eric M. Ferreira,
and Brian M. Stoltz. Angew. Chem. Int. Ed.
2003, 42, 2892. [Supporting
Information]
(This paper was featured on
organic-chemistry.org).
"Biomimetic
Approaches to Gas Phase Peptide Chemistry: Combining
Selective Binding Motifs with Reactive Carbene Precursors
to Form Molecular Mousetraps", Ryan R. Julian, Jeremy
A. May, Brian M. Stoltz, and J. L. Beauchamp. Int. J.
Mass Spectrom. 2003,
228(2-3), 851-64.
"Gas Phase Synthesis of Charged Copper
and Silver Fischer Carbenes from Diazomalonates:
Mechanistic and Conformational Considerations in Metal
Mediated Wolff Rearrangements", Ryan R. Julian,
Jeremy A. May, Brian M. Stoltz, and J. L. Beauchamp.
J. Am. Chem. Soc. 2003,
125, 4478.
"Molecular
Mousetraps: Gas Phase Studies of the Covalent Coupling of
Non-Covalent Complexes Initiated by Reactive Carbenes
Formed by Controlled Activation of Diazo Precursors",
Ryan R. Julian, Jeremy A. May, Brian M. Stoltz, and J. L.
Beauchamp. Angew. Chem. Int. Ed.
2003, 42, 1012.
[Cover], [Supporting
Information]
"Palladium-Catalyzed Enantioselective Oxidation of
Alcohols: A Dramatic Rate Acceleration by
Cs2CO3/t-BuOH", Jeffrey T.
Bagdanoff, Eric M. Ferreira, and Brian M. Stoltz.
Org. Lett. 2003, 5,
835. [Supporting
Information]
"Biomimetic
approach to communesin B (a.k.a. nomofungin)", Jeremy
A. May, Ryan K. Zeidan, and Brian M. Stoltz.
Tetrahedron Lett. 2003,
44, 1203.
"The First Total Synthesis of Dragmacidin
D", Neil K. Garg, Richmond Sarpong, and Brian M.
Stoltz. J. Am. Chem. Soc. 2002,
124, 13179. [Supporting
Information]
"Non-Carbonyl-Stabilized
Metallocarbenoids in Synthesis: The Development of a
Tandem Rhodium-Catalyzed Bamford-Stevens/Thermal
Aliphatic Claisen Rearrangement Sequence", Jeremy A.
May and Brian M. Stoltz. J. Am. Chem. Soc.
2002, 124, 12426. [Supporting
Information]
"Molecular
recognition of arginine in small peptides by
supramolecular complexation with dibenzo-30-crown-10
ether", Ryan R. Julian, Minta Akin, Jeremy A. May,
Brian M. Stoltz, and J. L. Beauchamp. Int. J. Mass
Spectrom. 2002, 220,
87.
"Progress Toward
the Synthesis of Garsubellin A and Related Phloroglucins:
The Direct Diastereoselective Synthesis of the
Bicyclo[3.3.1]nonane Core", Sarah J. Spessard and
Brian M. Stoltz. Org. Lett.
2002, 4, 1943. [Supporting
Information]
"The Palladium-Catalyzed Oxidative
Kinetic Resolution of Secondary Alcohols with Molecular
Oxygen", Eric M. Ferreira and Brian M. Stoltz. J.
Am. Chem. Soc. 2001, 123,
7725. [Supporting
Information]
"Total Synthesis of (±)-Phomoidride D", Joyce C. Leung, Aaron A. Bedermann, Jón T. Njardarson,David A. Spiegel, Graham K. Murphy, Naoto Hama, Barry M.Twenter, Ping Dong, Tatsuya Shirahata, Ivar M. McDonald,Munenori Inoue, Nobuaki Taniguchi, Travis C. McMahon,Christopher M. Schneider, Nancy Tao, Brian M. Stoltz, and John Wood Angew. Chem. Int. Ed.
2018, 57, 1991–1994.
"Welwitindolinone C synthetic studies. Construction of the welwitindolinone
carbon skeleton via a transannular nitrone cycloaddition", David B. Freeman, Alexandra A. Holubec, Matthew W. Weiss, Julie A.
Dixon, Akio Kakefuda, Masami Ohtsuka, Munenori Inoue, Rishi G. Vaswani, Hidenori
Ohki, Brian D. Doan, Sarah E. Reisman, Brian M. Stoltz, Joshua J. Day, Ran N. Tao,
Noah A. Dieterich, John L. Wood. Tetrahedron
2010, 66, 6647–6655.
"Synthesis of C(3)
Benzofuran-Derived Bisaryl Quaternary Centers: Approaches
to Diazonamide A", Douglas E. Fuerst, Brian M.
Stoltz, and John L. Wood. Org. Lett.
2000, 2, 3521. [Supporting
Information]
"Enantioselective Total Synthesis of
Nicandrenones", Brian M. Stoltz, Taichi Kano, and E.
J. Corey. J. Am. Chem. Soc.
2000, 122, 9044. [Supporting
Information]
"Mechanistic
Insights into the Factors Determining Exo-Endo
Selectivity in the Lewis Acid-Catalyzed Diels-Alder
Reaction of 1,3-Dienes with 2-Cycloalkenones", Min
Ge, Brian M. Stoltz, and E. J. Corey. Org. Lett.
2000, 2, 1927.
"Cuprous Chloride Accelerated Stille
Reactions. A General and Effective Coupling System for
Sterically Congested Substrates and for Enantioselective
Synthesis", Xiaojun Han, Brian M. Stoltz, and E. J.
Corey. J. Am. Chem. Soc. 1999,
121, 7600. [Supporting
Information]
"A Simple and
Effective Procedure for Removal of Tri-n-butyltin Halides
from Reaction Mixtures", Benjamin S. Edelson, Brian
M. Stoltz and E. J. Corey. Tetrahedron Lett.
1999, 40, 6729.
"Novel Annulation
Products Derived by Selective Attack on the C(18) Angular
Methyl Group of the Cardenolide Ouabain", E. J. Corey
and Brian M. Stoltz. Tetrahedron Lett.
1999, 40, 2061.
"Total Synthesis
and Protein Kinase Activity of C(7) Methyl Derivatives of
K252a", John L. Wood, Dejah T. Petsch, Brian M.
Stoltz, Elizabeth M. Hawkins, Daniel Elbaum, and David R.
Stover. Synthesis 1999,
Sup. 1, 1529.
"Application of Reactive Enols in
Synthesis: A Versatile Efficient and Stereoselective
Construction of the Welwitindolinone Carbon
Skeleton", John L. Wood, Alexandra A. Holubec, Brian
M. Stoltz, Matthew M. Weiss, Julie A. Dixon, Brian D.
Doan, Mohammed F. Shamji, Jennifer M. Chen, and Timothy
P. Heffron. J. Am. Chem. Soc.
1999, 121, 6326. [Supporting
Information]
"Development of a Rhodium
Carbenoid-Initiated Claisen Rearrangement for the
Enantioselective Synthesis of α-Hydroxy Carbonyl
Compounds", John L. Wood, George A. Moniz, Derek A.
Pflum, Brian M. Stoltz, Alexandra A. Holubec, and
Hans-Jürgen Dietrich. J. Am. Chem. Soc.
1999, 121, 1748. [Supporting
Information]
"The Design and Implementation of an
Efficient Synthetic Approach to Pyranosylated
Indolocarbazoles: The Total Synthesis of (+)-RK286c,
(+)-MLR-52, (+)-Staurosporine, and (-)-TAN-1030a",
John L. Wood, Brian M. Stoltz, Steven N. Goodman, and
Kenolisa Onwueme. J. Am. Chem. Soc.
1997, 119, 9652. [Supporting
Information]
"The Design and Implementation of an
Efficient Synthetic Approach to Furanosylated
Indolocarbazoles: The Total Synthesis of (+)- and
(-)-K252a", John L. Wood, Brian M. Stoltz,
Hans-Jürgen Dietrich, Derek A. Pflum, and Dejah T.
Petsch. J. Am. Chem. Soc. 1997,
119, 9641. [Supporting
Information]
"The Total
Synthesis of Indolocarbazole Natural Products K252c,
(+)-K252a, (+)-RK-286c, (+)-MLR-52, (-)-TAN-1030a, and
(+)-Staurosporine", Brian M. Stoltz, Ph.D. Thesis,
Yale University, May 1997.
"The Total Synthesis of (+)-RK-286c,
(+)-MLR-52, (+)-Staurosporine and (+)-K252a", John L.
Wood, Brian M. Stoltz, and Steven N. Goodman. J. Am.
Chem. Soc. 1996, 118,
10656. [Supporting
Information]. (This paper was featured in a
C&EN.
News of the Week article.)
"The Synthesis of
Desamido Analogs of Staurosporine, RK-286c, and
TAN-1030a. A Model for the Synthesis of Both
Furanosylated and Pyranosylated Indolocarbazole Natural
Products", John L. Wood, Brian M. Stoltz, Kenolisa
Onwueme and Steven N. Goodman. Tetrahedron Lett.
1996, 37, 7335.
"The
Stereoselective Ring Contraction of a Pyranosylated
Indolocarbazole. A Biosynthetic Link Between K252a and
Staurosporine?", Brian M. Stoltz and John L. Wood.
Tetrahedron Lett. 1996,
37, 3929.
"A Ring Expansion
Approach to Pyranosylated Indolocarbazoles", Brian M.
Stoltz and John L. Wood. Tetrahedron Lett.
1995, 36, 8543.
"The Total Synthesis of (+)- and
(-)-K252a", John L. Wood, Brian M. Stoltz, and
Hans-Jürgen Dietrich. J. Am. Chem. Soc.
1995, 117, 10413.
Patents
"Enantioselective Synthesis of α-Quaternary Mannich Adducts by Palladium-Catalyzed Allylic Alkylation", Brian M. Stoltz, Yoshitaka Numajiri, Beau P. Pritchett, and Koji Chiyoda. United States Patent US 10421696, 2019.
"Methods for Enantioselective Allylic Alkylation of Esters, Lactones and Lactams with Unactivated Allylic Alcohols", Brian M. Stoltz, Aurapat Ngamnithiporn, Carina I. Jette, Shoshana Bachman, Scott C. Virgil, and Sebastian Lackner. United States Patent US 10358422, 2019.
"Asymmetric Catalytic Decarboxylative Allylic Alkylation Using Low Catalyst Concentrations and a Robust Precatalyst", Brian M. Stoltz, Alexander N. Marziale, Robert A. Craig II, Douglas C. Duquette, Kelly E. Kim, Marc Liniger, and Yoshitaka Numajiri. United States Patent US 10106479, 2018.
"Preparation of Silylamines by the dehydrogenative Coupling of N–H and Si–H Bonds", Anton Toutov, Kerry Betz, Alexey Fedorov, Brian M. Stoltz, Wen-bo Liu, and Robert H. Grubbs. United States Patent US 10125153, 2018.
"Compositions and Methods for Acylating Lactams", Brian M. Stoltz, Masaki Hayashi, and Satoshi Hashimoto. United States Patent US 10040784, 2018.
"Base-Catalyzed Silylation of Terminal Olefinic C–H Bonds", Anton Toutov, Wen-bo Liu, Kerry Betz, Alexey Fedorov, Brian M. Stoltz, and Robert H. Grubbs. United States Patent US 10059726, 2018.
"Silylation of aromatic heterocycles by earth abundant transition-metal-free catalysts", Anton Toutov, Kerry Betz, Alexey Fedorov, Brian M. Stoltz, Wen-bo Liu, and Robert H. Grubbs. United States Patent US 9809607, 2017.
"Synthesis of Chiral Enaminones, Their Derivatives, and Bioactivity Studies Thereof", Brian M. Stoltz, Dennis A. Dougherty, Douglas Duquette, Noah Duffy. United States Patent US 9518034, 2017.
"Base-Catalyzed Silylation of Terminal Alkyne C-H Bonds", Anton A. Toutov; Kerry N. Betz; Brian M. Stoltz; Wenbo Liu; Robert H. Grubbs. United States Patent US 9556206, 2017.
"Silylation of Aromatic Heterocycles by Disilanes Using Potassium Alkoxide Catalysts", Anton A. Toutov; Wenbo Liu; Brian M. Stoltz; Robert H. Grubbs; Kerry N. Betz; David P. Schuman. United States Patent US 9556080, 2017.
"Palladium-catalyzed decarbonylation of fatty acid anhydrides for the production of linear alpha olefins", Yiyang Liu, Brian M. Stoltz, Robert H. Grubbs, Alexey Fedorov, and Kelly E. Kim. United States Patent US 9440891, 2016.
"Synthetic Transtaganolide and Basiliolide Products, Derivatives thereof, and Synthesis Methods Thereof", Hosea Nelson, Kei Murakami, Scott C. Virgil, Brian M. Stoltz, Jonathan R. Gordon. United States Patent US 9422259, 2016.
"Method of preparing Z-alkene-containing insect pheromones", Eric A. Bercot and Brian M. Stoltz. United States Patent US 9181164, 2015.
"Inhibitors of P97", Steven J. Brown, Tsui-Fen Chou, Raymond Deshaies, Amanda C. Jones, Hugh Rosen, Brian M. Stoltz. United States Patent US 9089572, 2015.
"Synthetic Transtaganolide and Basiliolide Products, Derivatives thereof, and Synthesis Methods Thereof", Hosea Nelson, Kei Murakami, Scott C. Virgil, Brian M. Stoltz, Jonathan R. Gordon. United States Patent US 8912347, 2014.
"Quaternary Heteroatom Containing Compounds,", Brian M. Stoltz, Scott C. Virgil, David E. White, Taiga Yurino, Yiyang Liu, Douglas C. Behenna, Douglas Duquette, and Christian Eidamshaus. United States Patent US 8822679, 2014.
"Liphagal Enantiomers and their Derivatives and Precursors, and Enantioselective Methods of Making the Same,", Brian M. Stoltz, Ryan McFadden, Scott C. Virgil, Helene Kolding, Jennifer L. Alleva, and Joshua J. Day United States Patent US 8653307, 2014.
"Certain Chemical Entities, Compositions, and Methods", Zhe Yang, Scott Collibee, Alex R. Muci, Jianchao Wang, Luke W. Ashcraft, Jeff Gardina, Brian M. Stoltz, Gustave Bergnes, and Bradley P. Morgan. United States Patent US 7989469, 2011.
"Enantioselective, Catalytic Allylation of Ketones and Olefins", Douglas C. Behenna, Brian M. Stoltz, Justin T. Mohr, Andrew M. Harned. United States Patent US 7235698, 2007.
"Methods and Compositions for Enantioselective Oxidation Reactions", Eric M. Ferreira, Brian M. Stoltz. United States Patent US 7166754, 2007.
"Chemical Reagents Capable of Selective Attachment to and Reaction with Peptides and Proteins", Jesse L. Beauchamp, Ryan R. Julian, Brian M. Stoltz and Jeremy A. May. United States Patent Application US 2005/0010059, 2005.
"Glycosylated Indolocarbazole Synthesis", John L. Wood, Brian M. Stoltz, Hans-Jürgen Dietrich, and Derek A. Pflum. Worldwide Patent WO 9707081, 1997. Also United States Patent US 7038043 and United States Patent US 6037468.